Stroke incidence and survival in the beginning of the 21st century in southern Sweden: comparisons with the late 20th century and projections into the future.
(2008) In Stroke: a journal of cerebral circulation 39(1). p.10-15- Abstract
- BACKGROUND AND PURPOSE: We report trends of stroke incidence and survival up to year 2001/2002 in Lund-Orup, Sweden, and projections of future stroke incidence in Sweden. METHODS: Lund Stroke Register, a prospective population-based study, included all first-ever stroke patients, between March 1, 2001 and February 28, 2002, in the Lund-Orup health care district. Institution-based studies for 1983 to 1985 and 1993 to 1995 were used for comparison. We calculated age-standardized incidence and Cox proportional hazards analysis of survival (stroke subtype, sex, age group, and study period in the analysis). Minimum follow-up was 46 months. Based on our register's stroke incidence and the official Swedish population projection, a projection for... (More)
- BACKGROUND AND PURPOSE: We report trends of stroke incidence and survival up to year 2001/2002 in Lund-Orup, Sweden, and projections of future stroke incidence in Sweden. METHODS: Lund Stroke Register, a prospective population-based study, included all first-ever stroke patients, between March 1, 2001 and February 28, 2002, in the Lund-Orup health care district. Institution-based studies for 1983 to 1985 and 1993 to 1995 were used for comparison. We calculated age-standardized incidence and Cox proportional hazards analysis of survival (stroke subtype, sex, age group, and study period in the analysis). Minimum follow-up was 46 months. Based on our register's stroke incidence and the official Swedish population projection, a projection for future stroke incidence on a national basis was calculated. RESULTS: We included 456 patients with first-ever stroke in 2001/2002. The age-standardized incidence (to the European population) was 144 per 100 000 person-years (95%CI 130 to 158) in 2001/2002, 158 (95%CI 149 to 168) in 1993 to 1995, and 134 (95%CI 126 to 143) in 1983 to 1985. Cox proportional hazard analysis indicated decreased risk of death after stroke in 2001/2002 (hazard ratio 0.80; 95%CI 0.67 to 0.94) compared with 1993 to 1995. Up to year 2050, the annual number of new stroke patients in Sweden may increase by 59% based solely on demographic changes. CONCLUSIONS: Despite possible underestimation of stroke incidence during the previous institution-based studies, the increased stroke incidence between 1983 to 1985 and 1993 to 1995 did not continue in 2001/2002. The long-term survival after stroke continues to improve. As the elderly population is growing in Sweden, stable incidence and increasing survival will result in a rapidly increasing prevalence of stroke patients in Sweden. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1035544
- author
- Hallström, Björn LU ; Jönsson, Ann-Cathrin LU ; Nerbrand, Christina LU ; Norrving, Bo LU and Lindgren, Arne LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- survival, stroke, projection, epidemiology, incidence, population-based, case-fatality
- in
- Stroke: a journal of cerebral circulation
- volume
- 39
- issue
- 1
- pages
- 10 - 15
- publisher
- American Heart Association
- external identifiers
-
- pmid:18063825
- wos:000251924600005
- scopus:38149042130
- pmid:18063825
- ISSN
- 1524-4628
- DOI
- 10.1161/STROKEAHA.107.491779
- language
- English
- LU publication?
- yes
- id
- f56e12fb-f1bb-4e8e-ba22-fca0bcb5a3cb (old id 1035544)
- date added to LUP
- 2016-04-01 14:16:47
- date last changed
- 2022-04-22 02:18:15
@article{f56e12fb-f1bb-4e8e-ba22-fca0bcb5a3cb,
abstract = {{BACKGROUND AND PURPOSE: We report trends of stroke incidence and survival up to year 2001/2002 in Lund-Orup, Sweden, and projections of future stroke incidence in Sweden. METHODS: Lund Stroke Register, a prospective population-based study, included all first-ever stroke patients, between March 1, 2001 and February 28, 2002, in the Lund-Orup health care district. Institution-based studies for 1983 to 1985 and 1993 to 1995 were used for comparison. We calculated age-standardized incidence and Cox proportional hazards analysis of survival (stroke subtype, sex, age group, and study period in the analysis). Minimum follow-up was 46 months. Based on our register's stroke incidence and the official Swedish population projection, a projection for future stroke incidence on a national basis was calculated. RESULTS: We included 456 patients with first-ever stroke in 2001/2002. The age-standardized incidence (to the European population) was 144 per 100 000 person-years (95%CI 130 to 158) in 2001/2002, 158 (95%CI 149 to 168) in 1993 to 1995, and 134 (95%CI 126 to 143) in 1983 to 1985. Cox proportional hazard analysis indicated decreased risk of death after stroke in 2001/2002 (hazard ratio 0.80; 95%CI 0.67 to 0.94) compared with 1993 to 1995. Up to year 2050, the annual number of new stroke patients in Sweden may increase by 59% based solely on demographic changes. CONCLUSIONS: Despite possible underestimation of stroke incidence during the previous institution-based studies, the increased stroke incidence between 1983 to 1985 and 1993 to 1995 did not continue in 2001/2002. The long-term survival after stroke continues to improve. As the elderly population is growing in Sweden, stable incidence and increasing survival will result in a rapidly increasing prevalence of stroke patients in Sweden.}},
author = {{Hallström, Björn and Jönsson, Ann-Cathrin and Nerbrand, Christina and Norrving, Bo and Lindgren, Arne}},
issn = {{1524-4628}},
keywords = {{survival; stroke; projection; epidemiology; incidence; population-based; case-fatality}},
language = {{eng}},
number = {{1}},
pages = {{10--15}},
publisher = {{American Heart Association}},
series = {{Stroke: a journal of cerebral circulation}},
title = {{Stroke incidence and survival in the beginning of the 21st century in southern Sweden: comparisons with the late 20th century and projections into the future.}},
url = {{http://dx.doi.org/10.1161/STROKEAHA.107.491779}},
doi = {{10.1161/STROKEAHA.107.491779}},
volume = {{39}},
year = {{2008}},
}