Organization of the ferret lateral cervical nucleus and cervicothalamic tract.
(2002) In Somatosensory & Motor Research 19(1). p.36-48- Abstract
- To elucidate the organization of the ferret spinocervicothalamic pathway (SCTP), we examined the lateral cervical nucleus (LCN) and the termination of the cervicothalamic tract (CTY) in this species. In thionin-stained sections, the ferret LCN appeared as an easily delineated column of cells in the dorsolateral funiculus from about mid-C3 to the rostral end of C1, with most cells located in the C1 and C2 segments. In transverse sections, the LCN was elongated along a dorsolateral to ventromedial axis and in the rostral half of C2 and caudal half of C1 continuous with the neck of the dorsal horn. The number of ferret LCN cells was estimated to 2,500-3,700, with an average of 3,340. Substance P-like immunoreactive fibers located... (More)
- To elucidate the organization of the ferret spinocervicothalamic pathway (SCTP), we examined the lateral cervical nucleus (LCN) and the termination of the cervicothalamic tract (CTY) in this species. In thionin-stained sections, the ferret LCN appeared as an easily delineated column of cells in the dorsolateral funiculus from about mid-C3 to the rostral end of C1, with most cells located in the C1 and C2 segments. In transverse sections, the LCN was elongated along a dorsolateral to ventromedial axis and in the rostral half of C2 and caudal half of C1 continuous with the neck of the dorsal horn. The number of ferret LCN cells was estimated to 2,500-3,700, with an average of 3,340. Substance P-like immunoreactive fibers located preferentially in the ventromedial part of the LCN, whereas serotonin-like immunoreactive fibers were found throughout the nucleus. Anterograde transport of wheat germ agglutinin-horseradish peroxidase conjugate and biotinylated dextran amine demonstrated that the ferret CTT terminates extensively in the peripheral parts of the ventral posterior lateral nucleus. Sparser termination was evident in the ventral posterior inferior nucleus, in the medial nucleus of the posterior complex, and in the medial part of the magnocellular medial geniculate nucleus. Thus, although the LCN is significantly smaller in ferrets than in cats and raccoons, the organization of the LCN and of the cervicothalamic tract is closely similar in the three species. These findings indicate a conserved general organization of the SCTP among carnivores. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/107742
- author
- Zhang, Mengliang LU ; Liu, Yi LU and Broman, Jonas LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Somatosensory & Motor Research
- volume
- 19
- issue
- 1
- pages
- 36 - 48
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:11962645
- wos:000175114500005
- scopus:0036217402
- ISSN
- 0899-0220
- DOI
- 10.1080/08990220120113039
- language
- English
- LU publication?
- yes
- id
- 542cbdbf-6e79-4f1f-a4f9-b2dbe20601fc (old id 107742)
- alternative location
- http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11962645&dopt=Abstract
- date added to LUP
- 2016-04-01 12:08:44
- date last changed
- 2022-01-26 23:25:18
@article{542cbdbf-6e79-4f1f-a4f9-b2dbe20601fc,
abstract = {{To elucidate the organization of the ferret spinocervicothalamic pathway (SCTP), we examined the lateral cervical nucleus (LCN) and the termination of the cervicothalamic tract (CTY) in this species. In thionin-stained sections, the ferret LCN appeared as an easily delineated column of cells in the dorsolateral funiculus from about mid-C3 to the rostral end of C1, with most cells located in the C1 and C2 segments. In transverse sections, the LCN was elongated along a dorsolateral to ventromedial axis and in the rostral half of C2 and caudal half of C1 continuous with the neck of the dorsal horn. The number of ferret LCN cells was estimated to 2,500-3,700, with an average of 3,340. Substance P-like immunoreactive fibers located preferentially in the ventromedial part of the LCN, whereas serotonin-like immunoreactive fibers were found throughout the nucleus. Anterograde transport of wheat germ agglutinin-horseradish peroxidase conjugate and biotinylated dextran amine demonstrated that the ferret CTT terminates extensively in the peripheral parts of the ventral posterior lateral nucleus. Sparser termination was evident in the ventral posterior inferior nucleus, in the medial nucleus of the posterior complex, and in the medial part of the magnocellular medial geniculate nucleus. Thus, although the LCN is significantly smaller in ferrets than in cats and raccoons, the organization of the LCN and of the cervicothalamic tract is closely similar in the three species. These findings indicate a conserved general organization of the SCTP among carnivores.}},
author = {{Zhang, Mengliang and Liu, Yi and Broman, Jonas}},
issn = {{0899-0220}},
language = {{eng}},
number = {{1}},
pages = {{36--48}},
publisher = {{Taylor & Francis}},
series = {{Somatosensory & Motor Research}},
title = {{Organization of the ferret lateral cervical nucleus and cervicothalamic tract.}},
url = {{http://dx.doi.org/10.1080/08990220120113039}},
doi = {{10.1080/08990220120113039}},
volume = {{19}},
year = {{2002}},
}