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Direct evidence for the cytomembrane derivation of Birbeck granules: the membrane-sandwich effect

Bartosik, Jacek LU ; Andersson, A ; Axelsson, S ; Falck, B and Ringberg, Anita LU (1985) In Acta Dermato-Venereologica 65(2). p.157-160
Abstract
Digitonin, which is known to cause extensive damage to cytomembranes in general, was found to have a most remarkable effect on epidermal Langerhans' cells. Thus, it generates a membrane-sandwiching process resulting in the formation of large discs which except for the differences in size have the same morphology as ordinary Birbeck granules. This demonstrates that the cytomembrane of the Langerhans' cell has the inherent ability to superimpose upon itself, leaving little doubt that the normal Birbeck granules derive from the cytomembrane.
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
65
issue
2
pages
157 - 160
publisher
Medical Journals Limited
external identifiers
  • pmid:2408420
  • scopus:0022001703
ISSN
1651-2057
language
English
LU publication?
yes
id
664cfdd3-2adc-4909-bcee-585e38bf4e9c (old id 1103379)
date added to LUP
2016-04-01 15:56:25
date last changed
2021-08-29 04:23:32
@article{664cfdd3-2adc-4909-bcee-585e38bf4e9c,
  abstract     = {{Digitonin, which is known to cause extensive damage to cytomembranes in general, was found to have a most remarkable effect on epidermal Langerhans' cells. Thus, it generates a membrane-sandwiching process resulting in the formation of large discs which except for the differences in size have the same morphology as ordinary Birbeck granules. This demonstrates that the cytomembrane of the Langerhans' cell has the inherent ability to superimpose upon itself, leaving little doubt that the normal Birbeck granules derive from the cytomembrane.}},
  author       = {{Bartosik, Jacek and Andersson, A and Axelsson, S and Falck, B and Ringberg, Anita}},
  issn         = {{1651-2057}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{157--160}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Direct evidence for the cytomembrane derivation of Birbeck granules: the membrane-sandwich effect}},
  volume       = {{65}},
  year         = {{1985}},
}