Ultrasound nucleolysis: an in vitro study.
(2002) In Ultrasound in Medicine and Biology 28(9). p.1189-1197- Abstract
- Thermal intradiscal therapy for chronic low back pain, using a catheter inserted into the intervertebral disc, is becoming more popular in the treatment of low back pain. The aim of this study was to investigate the possibility of heating the nucleus pulposus of the intervertebral disc with high-intensity focused ultrasound (US) or HIFU. Two specific situations were considered, invasive transducers that would be in contact with the annulus fibrosus of the disc, and noninvasive transducers that could be used externally. Theoretical simulations were performed to find the optimal parameters of US transducers and then experimental studies were done using transducers made to these specifications. These experiments confirmed that it was possible... (More)
- Thermal intradiscal therapy for chronic low back pain, using a catheter inserted into the intervertebral disc, is becoming more popular in the treatment of low back pain. The aim of this study was to investigate the possibility of heating the nucleus pulposus of the intervertebral disc with high-intensity focused ultrasound (US) or HIFU. Two specific situations were considered, invasive transducers that would be in contact with the annulus fibrosus of the disc, and noninvasive transducers that could be used externally. Theoretical simulations were performed to find the optimal parameters of US transducers and then experimental studies were done using transducers made to these specifications. These experiments confirmed that it was possible to heat the discs with HIFU. Two orthogonal transducers resulted in a superior temperature distribution than using just one transducer. It is, therefore, feasible to consider thermal treatment of the nucleus pulposus of the disc using noninvasive US. (E-mail: Johan.Persson@ort.lu.se) (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/110491
- author
- Persson, Johan K LU ; Strömqvist, Björn LU ; Zanoli, Gustavo LU ; McCarthy, Ian LU and Lidgren, Lars LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Ultrasound in Medicine and Biology
- volume
- 28
- issue
- 9
- pages
- 1189 - 1197
- publisher
- Elsevier
- external identifiers
-
- wos:000178732200013
- pmid:12401390
- scopus:0036750206
- ISSN
- 0301-5629
- DOI
- 10.1016/S0301-5629(02)00566-5
- language
- English
- LU publication?
- yes
- id
- 07e9e95b-d843-4bb4-a61c-90c578fc4a24 (old id 110491)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12401390&dopt=Abstract
- date added to LUP
- 2016-04-01 11:50:33
- date last changed
- 2022-01-26 19:03:32
@article{07e9e95b-d843-4bb4-a61c-90c578fc4a24,
abstract = {{Thermal intradiscal therapy for chronic low back pain, using a catheter inserted into the intervertebral disc, is becoming more popular in the treatment of low back pain. The aim of this study was to investigate the possibility of heating the nucleus pulposus of the intervertebral disc with high-intensity focused ultrasound (US) or HIFU. Two specific situations were considered, invasive transducers that would be in contact with the annulus fibrosus of the disc, and noninvasive transducers that could be used externally. Theoretical simulations were performed to find the optimal parameters of US transducers and then experimental studies were done using transducers made to these specifications. These experiments confirmed that it was possible to heat the discs with HIFU. Two orthogonal transducers resulted in a superior temperature distribution than using just one transducer. It is, therefore, feasible to consider thermal treatment of the nucleus pulposus of the disc using noninvasive US. (E-mail: Johan.Persson@ort.lu.se)}},
author = {{Persson, Johan K and Strömqvist, Björn and Zanoli, Gustavo and McCarthy, Ian and Lidgren, Lars}},
issn = {{0301-5629}},
language = {{eng}},
number = {{9}},
pages = {{1189--1197}},
publisher = {{Elsevier}},
series = {{Ultrasound in Medicine and Biology}},
title = {{Ultrasound nucleolysis: an in vitro study.}},
url = {{http://dx.doi.org/10.1016/S0301-5629(02)00566-5}},
doi = {{10.1016/S0301-5629(02)00566-5}},
volume = {{28}},
year = {{2002}},
}