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Beta camera low activity tumor imaging

Ljunggren, Kaj LU ; Strand, Sven-Erik LU ; Ceberg, Crister LU orcid ; Sjöholm, Hans ; Elmqvist, Dan ; Brun, Arne LU and Salford, Leif LU (1993) In Acta Oncologica 32(7-8). p.869-872
Abstract
A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity... (More)
A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns. (Less)
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Oncologica
volume
32
issue
7-8
pages
869 - 872
publisher
Taylor & Francis
external identifiers
  • pmid:8305238
  • scopus:0027716103
ISSN
1651-226X
DOI
10.3109/02841869309096148
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Radiation Physics, Lund (013034000), Neurosurgery (013026000), Pathology, (Lund) (013030000)
id
2ea0f501-15e5-4dbe-a2f4-14bae7ead844 (old id 1107461)
date added to LUP
2016-04-01 15:27:10
date last changed
2021-01-03 04:01:47
@article{2ea0f501-15e5-4dbe-a2f4-14bae7ead844,
  abstract     = {{A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns.}},
  author       = {{Ljunggren, Kaj and Strand, Sven-Erik and Ceberg, Crister and Sjöholm, Hans and Elmqvist, Dan and Brun, Arne and Salford, Leif}},
  issn         = {{1651-226X}},
  language     = {{eng}},
  number       = {{7-8}},
  pages        = {{869--872}},
  publisher    = {{Taylor & Francis}},
  series       = {{Acta Oncologica}},
  title        = {{Beta camera low activity tumor imaging}},
  url          = {{http://dx.doi.org/10.3109/02841869309096148}},
  doi          = {{10.3109/02841869309096148}},
  volume       = {{32}},
  year         = {{1993}},
}