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Lipopolysaccharide (LPS) inhalation in healthy subjects causes bronchoalveolar neutrophilia, lymphocytosis, and fibronectin increase

Sandstrom, Thomas ; Bjermer, Leif LU and Rylander, Ragnar (1994) In American Journal of Industrial Medicine 25(1). p.103-104
Abstract
Eight healthy volunteers were exposed to purified lipopolysaccharide (LPS) by controlled inhalation. Bronchoalveolar lavage (BAL) 3 hours after exposure revealed a pronounced neutrophilia, increase in lymphocytes, fibronectin concentration, and decrease in alveolar macrophage phagocytosis, as compared to a reference BAL.
Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
organic dusts, inflammation, endotoxins, BAL, inhalational exposures
in
American Journal of Industrial Medicine
volume
25
issue
1
pages
103 - 104
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:8116630
  • scopus:0028013287
ISSN
0271-3586
DOI
10.1002/ajim.4700250127
language
English
LU publication?
no
id
0f41cef3-c349-4207-abc5-7c5a8aaad292 (old id 1107833)
date added to LUP
2016-04-01 11:38:38
date last changed
2021-01-03 10:09:26
@article{0f41cef3-c349-4207-abc5-7c5a8aaad292,
  abstract     = {{Eight healthy volunteers were exposed to purified lipopolysaccharide (LPS) by controlled inhalation. Bronchoalveolar lavage (BAL) 3 hours after exposure revealed a pronounced neutrophilia, increase in lymphocytes, fibronectin concentration, and decrease in alveolar macrophage phagocytosis, as compared to a reference BAL.}},
  author       = {{Sandstrom, Thomas and Bjermer, Leif and Rylander, Ragnar}},
  issn         = {{0271-3586}},
  keywords     = {{organic dusts; inflammation; endotoxins; BAL; inhalational exposures}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{103--104}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{American Journal of Industrial Medicine}},
  title        = {{Lipopolysaccharide (LPS) inhalation in healthy subjects causes bronchoalveolar neutrophilia, lymphocytosis, and fibronectin increase}},
  url          = {{http://dx.doi.org/10.1002/ajim.4700250127}},
  doi          = {{10.1002/ajim.4700250127}},
  volume       = {{25}},
  year         = {{1994}},
}