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High-frequency components in ECG analysed in guinea-pig Langendorf preparations

Bennhagen, Rolf LU ; Sörnmo, Leif LU ; Pesonen, Erkki LU and Wohlfart, Björn LU (2001) In Clinical Physiology 21(5). p.576-583
Abstract
High-frequency components in ECG during global ischaemia were studied in isolated guinea-pig hearts perfused ad modum Langendorf. Electrocardiograph recordings were carried out from the epicardial surface both in normo- and low-flow perfusion. After bandpass filtering (5-500 Hz), signal-averaging, was undertaken. The high-frequency components either increased or decreased after low-flow perfusion was instituted. Root-mean-square voltage (RMS) of the depolarization signal correlated poorly with the signal amplitude, but highly with the first and second derivative, i.e. the velocity and the acceleration of the signal. It is concluded that high-frequency components are not pathological phenomena per se, but reflect the shape of the original... (More)
High-frequency components in ECG during global ischaemia were studied in isolated guinea-pig hearts perfused ad modum Langendorf. Electrocardiograph recordings were carried out from the epicardial surface both in normo- and low-flow perfusion. After bandpass filtering (5-500 Hz), signal-averaging, was undertaken. The high-frequency components either increased or decreased after low-flow perfusion was instituted. Root-mean-square voltage (RMS) of the depolarization signal correlated poorly with the signal amplitude, but highly with the first and second derivative, i.e. the velocity and the acceleration of the signal. It is concluded that high-frequency components are not pathological phenomena per se, but reflect the shape of the original electrocardiographic signal. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Clinical Physiology
volume
21
issue
5
pages
576 - 583
publisher
John Wiley & Sons Inc.
external identifiers
  • wos:000171605100009
  • scopus:0034780890
ISSN
1365-2281
DOI
10.1046/j.1365-2281.2001.00368.x
language
English
LU publication?
yes
id
5d02301f-3cfe-4448-bf36-931822c0b176 (old id 1118827)
date added to LUP
2016-04-01 11:45:29
date last changed
2022-03-28 02:42:35
@article{5d02301f-3cfe-4448-bf36-931822c0b176,
  abstract     = {{High-frequency components in ECG during global ischaemia were studied in isolated guinea-pig hearts perfused ad modum Langendorf. Electrocardiograph recordings were carried out from the epicardial surface both in normo- and low-flow perfusion. After bandpass filtering (5-500 Hz), signal-averaging, was undertaken. The high-frequency components either increased or decreased after low-flow perfusion was instituted. Root-mean-square voltage (RMS) of the depolarization signal correlated poorly with the signal amplitude, but highly with the first and second derivative, i.e. the velocity and the acceleration of the signal. It is concluded that high-frequency components are not pathological phenomena per se, but reflect the shape of the original electrocardiographic signal.}},
  author       = {{Bennhagen, Rolf and Sörnmo, Leif and Pesonen, Erkki and Wohlfart, Björn}},
  issn         = {{1365-2281}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{576--583}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Clinical Physiology}},
  title        = {{High-frequency components in ECG analysed in guinea-pig Langendorf preparations}},
  url          = {{http://dx.doi.org/10.1046/j.1365-2281.2001.00368.x}},
  doi          = {{10.1046/j.1365-2281.2001.00368.x}},
  volume       = {{21}},
  year         = {{2001}},
}