D-dimer testing in patients with suspected acute thromboembolic occlusion of the superior mesenteric artery
Acosta, Stefan LU
; Nilsson, T K
and Bjorck, M
(2004)
In British Journal of Surgery
91(8).
p.991-994
- Abstract
- BACKGROUND: There is no accurate non-invasive method available for the diagnosis of acute thromboembolic occlusion of the superior mesenteric artery (SMA). The aim of this study was to assess the diagnostic properties of the fibrinolytic marker D-dimer. METHODS: From September 2000 to April 2003 consecutive patients aged over 50 years admitted to hospital with acute abdominal pain were studied. Patients with possible acute SMA occlusion at presentation had blood samples taken within 24 h of the onset of the pain for analysis of D-dimer, plasma fibrinogen, activated partial thromboplastin time, prothrombin time and antithrombin. The value of D-dimer testing to diagnose SMA occlusion was assessed by means of likelihood ratios. RESULTS: Nine... (More)
- BACKGROUND: There is no accurate non-invasive method available for the diagnosis of acute thromboembolic occlusion of the superior mesenteric artery (SMA). The aim of this study was to assess the diagnostic properties of the fibrinolytic marker D-dimer. METHODS: From September 2000 to April 2003 consecutive patients aged over 50 years admitted to hospital with acute abdominal pain were studied. Patients with possible acute SMA occlusion at presentation had blood samples taken within 24 h of the onset of the pain for analysis of D-dimer, plasma fibrinogen, activated partial thromboplastin time, prothrombin time and antithrombin. The value of D-dimer testing to diagnose SMA occlusion was assessed by means of likelihood ratios. RESULTS: Nine of 101 patients included had acute SMA occlusion. The median D-dimer concentration was 1.6 (range 0.4-5.6) mg/l, which was higher than that in 25 patients with inflammatory disease (P = 0.007) or in 14 patients with intestinal obstruction (P = 0.005). The combination of a D-dimer level greater than 1.5 mg/l, atrial fibrillation and female sex resulted in a likelihood ratio for acute SMA occlusion of 17.5, whereas no patient with a D-dimer concentration of 0.3 mg/l or less had acute SMA occlusion. CONCLUSION: D-dimer testing may be useful for the exclusion of patients with suspected acute SMA occlusion. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1130866
- author
- Acosta, Stefan
LU
; Nilsson, T K
and Bjorck, M
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Surgery
- volume
- 91
- issue
- 8
- pages
- 991 - 994
- publisher
- Oxford University Press
- external identifiers
-
- pmid:15286959
- scopus:4043082730
- ISSN
- 1365-2168
- DOI
- 10.1002/bjs.4645
- language
- English
- LU publication?
- no
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200)
- id
- 48a97be5-b5d2-4309-a65c-f62cc9671803 (old id 1130866)
- date added to LUP
- 2016-04-01 12:38:42
- date last changed
- 2022-03-21 07:10:43
@article{48a97be5-b5d2-4309-a65c-f62cc9671803,
abstract = {{BACKGROUND: There is no accurate non-invasive method available for the diagnosis of acute thromboembolic occlusion of the superior mesenteric artery (SMA). The aim of this study was to assess the diagnostic properties of the fibrinolytic marker D-dimer. METHODS: From September 2000 to April 2003 consecutive patients aged over 50 years admitted to hospital with acute abdominal pain were studied. Patients with possible acute SMA occlusion at presentation had blood samples taken within 24 h of the onset of the pain for analysis of D-dimer, plasma fibrinogen, activated partial thromboplastin time, prothrombin time and antithrombin. The value of D-dimer testing to diagnose SMA occlusion was assessed by means of likelihood ratios. RESULTS: Nine of 101 patients included had acute SMA occlusion. The median D-dimer concentration was 1.6 (range 0.4-5.6) mg/l, which was higher than that in 25 patients with inflammatory disease (P = 0.007) or in 14 patients with intestinal obstruction (P = 0.005). The combination of a D-dimer level greater than 1.5 mg/l, atrial fibrillation and female sex resulted in a likelihood ratio for acute SMA occlusion of 17.5, whereas no patient with a D-dimer concentration of 0.3 mg/l or less had acute SMA occlusion. CONCLUSION: D-dimer testing may be useful for the exclusion of patients with suspected acute SMA occlusion.}},
author = {{Acosta, Stefan and Nilsson, T K and Bjorck, M}},
issn = {{1365-2168}},
language = {{eng}},
number = {{8}},
pages = {{991--994}},
publisher = {{Oxford University Press}},
series = {{British Journal of Surgery}},
title = {{D-dimer testing in patients with suspected acute thromboembolic occlusion of the superior mesenteric artery}},
url = {{http://dx.doi.org/10.1002/bjs.4645}},
doi = {{10.1002/bjs.4645}},
volume = {{91}},
year = {{2004}},
}