Orthostatic hypotension in organic dementia: relationship between blood pressure, cortical blood flow and symptoms
(1996) In Clinical autonomic research : official journal of the Clinical Autonomic Research Society 6(1). p.29-36- Abstract
- Regional cerebral blood flow was measured in 35 patients with organic dementia (Alzheimer's disease, n = 13, vascular dementia, n = 17, frontotemporal dementia, n = 5) and orthostatic hypotension. Measurements were performed during supine rest and during head-up tilt (60 degrees). Despite marked blood pressure falls, few patients had symptoms of orthostatic hypotension. All three dementia groups had a decrease in regional cerebral blood flow in the frontal lobes during head-up tilt, but no change in mean hemispheric flow. All patients had a consistent drop in their systolic blood pressure upon head-up tilt, with a wide variation over time. The findings suggest that orthostatic hypotension needs to be considered, and actively sought for, in... (More)
- Regional cerebral blood flow was measured in 35 patients with organic dementia (Alzheimer's disease, n = 13, vascular dementia, n = 17, frontotemporal dementia, n = 5) and orthostatic hypotension. Measurements were performed during supine rest and during head-up tilt (60 degrees). Despite marked blood pressure falls, few patients had symptoms of orthostatic hypotension. All three dementia groups had a decrease in regional cerebral blood flow in the frontal lobes during head-up tilt, but no change in mean hemispheric flow. All patients had a consistent drop in their systolic blood pressure upon head-up tilt, with a wide variation over time. The findings suggest that orthostatic hypotension needs to be considered, and actively sought for, in organic dementia as many patients may lack the typical symptoms of orthostatic hypotension, despite a marked fall in blood pressure. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1296397
- author
- Passant, Ulla LU ; Warkentin, Siegbert LU ; Karlson, S ; Nilsson, Karin LU ; Edvinsson, Lars LU and Gustafson, Lars LU
- organization
- publishing date
- 1996
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical autonomic research : official journal of the Clinical Autonomic Research Society
- volume
- 6
- issue
- 1
- pages
- 29 - 36
- publisher
- Springer
- external identifiers
-
- scopus:0029935468
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Faculty of Medicine (000022000), Department of Child and Youth Psychiatry (013303003), Clinical Memory Research Unit (013242610), Medicine (Lund) (013230025), Department of Psychogeriatrics (013304000)
- id
- 98d9cea5-3522-4bcf-b29f-ca695481a386 (old id 1296397)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed?term=Orthostatic%20hypotension%20in%20organic%20dementia%3A%20relationship%20between%20blood%20pressure%2C%20cortical%20blood%20flow%20and%20symptoms
- date added to LUP
- 2016-04-04 14:34:33
- date last changed
- 2024-01-04 00:25:40
@article{98d9cea5-3522-4bcf-b29f-ca695481a386,
abstract = {{Regional cerebral blood flow was measured in 35 patients with organic dementia (Alzheimer's disease, n = 13, vascular dementia, n = 17, frontotemporal dementia, n = 5) and orthostatic hypotension. Measurements were performed during supine rest and during head-up tilt (60 degrees). Despite marked blood pressure falls, few patients had symptoms of orthostatic hypotension. All three dementia groups had a decrease in regional cerebral blood flow in the frontal lobes during head-up tilt, but no change in mean hemispheric flow. All patients had a consistent drop in their systolic blood pressure upon head-up tilt, with a wide variation over time. The findings suggest that orthostatic hypotension needs to be considered, and actively sought for, in organic dementia as many patients may lack the typical symptoms of orthostatic hypotension, despite a marked fall in blood pressure.}},
author = {{Passant, Ulla and Warkentin, Siegbert and Karlson, S and Nilsson, Karin and Edvinsson, Lars and Gustafson, Lars}},
language = {{eng}},
number = {{1}},
pages = {{29--36}},
publisher = {{Springer}},
series = {{Clinical autonomic research : official journal of the Clinical Autonomic Research Society}},
title = {{Orthostatic hypotension in organic dementia: relationship between blood pressure, cortical blood flow and symptoms}},
url = {{http://www.ncbi.nlm.nih.gov/pubmed?term=Orthostatic%20hypotension%20in%20organic%20dementia%3A%20relationship%20between%20blood%20pressure%2C%20cortical%20blood%20flow%20and%20symptoms}},
volume = {{6}},
year = {{1996}},
}