Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction
Llona-Minguez, Sabin ; Throup, Adam ; Steiner, Emilie ; Lightowler, Molly ; Van der Haegen, Sandra ; Homan, Evert ; Eriksson, Lars ; Stenmark, Pål LU
; Jenmalm-Jensen, Annika
and Helleday, Thomas
(2017)
In Organic and Biomolecular Chemistry
15(37).
p.7758-7764
- Abstract
Here we present a two-step diastereoselective methodology building on a multicomponent aza-Diels-Alder reaction. Using previously unexplored cyclic ketones, heterocyclic amines and cyclopentadiene derivatives, we obtained novel spiro-heterocyclic frameworks at the interphase between "drug-like" molecules and natural products.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/13f6ae0c-483a-4624-8a59-aa735f7c2dd5
- author
- Llona-Minguez, Sabin
; Throup, Adam
; Steiner, Emilie
; Lightowler, Molly
; Van der Haegen, Sandra
; Homan, Evert
; Eriksson, Lars
; Stenmark, Pål
LU
; Jenmalm-Jensen, Annika
and Helleday, Thomas
- publishing date
- 2017-09-26
- type
- Contribution to journal
- publication status
- published
- in
- Organic and Biomolecular Chemistry
- volume
- 15
- issue
- 37
- pages
- 7758 - 7764
- publisher
- Royal Society of Chemistry
- external identifiers
-
- scopus:85030222551
- pmid:28891572
- ISSN
- 1477-0539
- DOI
- 10.1039/c7ob02069d
- language
- English
- LU publication?
- no
- id
- 13f6ae0c-483a-4624-8a59-aa735f7c2dd5
- date added to LUP
- 2019-04-30 07:54:13
- date last changed
- 2024-02-14 22:46:49
@article{13f6ae0c-483a-4624-8a59-aa735f7c2dd5,
abstract = {{<p>Here we present a two-step diastereoselective methodology building on a multicomponent aza-Diels-Alder reaction. Using previously unexplored cyclic ketones, heterocyclic amines and cyclopentadiene derivatives, we obtained novel spiro-heterocyclic frameworks at the interphase between "drug-like" molecules and natural products.</p>}},
author = {{Llona-Minguez, Sabin and Throup, Adam and Steiner, Emilie and Lightowler, Molly and Van der Haegen, Sandra and Homan, Evert and Eriksson, Lars and Stenmark, Pål and Jenmalm-Jensen, Annika and Helleday, Thomas}},
issn = {{1477-0539}},
language = {{eng}},
month = {{09}},
number = {{37}},
pages = {{7758--7764}},
publisher = {{Royal Society of Chemistry}},
series = {{Organic and Biomolecular Chemistry}},
title = {{Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction}},
url = {{http://dx.doi.org/10.1039/c7ob02069d}},
doi = {{10.1039/c7ob02069d}},
volume = {{15}},
year = {{2017}},
}