Carvone Contact Allergy in Southern Sweden : A 21-year Retrospective Study
(2018) In Acta Dermato-Venereologica 98(10). p.938-942- Abstract
Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, were studied. Carvone-positive and carvone-negative patients were compared regarding patch test data from baseline series and dental series. Dental series-tested carvone-positive patients were also compared with a matched group. A total of 147 out of 4,221 referred patients had a positive patch test to carvone. Sensitized patients had higher mean... (More)
Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, were studied. Carvone-positive and carvone-negative patients were compared regarding patch test data from baseline series and dental series. Dental series-tested carvone-positive patients were also compared with a matched group. A total of 147 out of 4,221 referred patients had a positive patch test to carvone. Sensitized patients had higher mean age and were primarily women; 73% had oral signs and 57% had oral lichen. Concomitant patch test reactions to gold, nickel and mercury were common. In the matched group-comparison carvone-positive patients had a higher frequency of oral lichen, but no difference was found in sensitization to gold and mercury.
(Less)
- author
- Kroona, Liv ; Isaksson, Marléne LU ; Ahlgren, Camilla ; Dahlin, Jakob LU ; Bruze, Magnus LU and Warfvinge, Gunnar
- organization
- publishing date
- 2018-11-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- l-carvoneCAS:6485-40-1, patchtest:allergens:contactallergy:orallichenplanus:orallichenoidlesions, spearmint
- in
- Acta Dermato-Venereologica
- volume
- 98
- issue
- 10
- pages
- 5 pages
- publisher
- Medical Journals Limited
- external identifiers
-
- scopus:85056285172
- pmid:30085320
- ISSN
- 1651-2057
- DOI
- 10.2340/00015555-3009
- language
- English
- LU publication?
- yes
- id
- 1422d141-e9ab-4c11-9453-6332873ec724
- date added to LUP
- 2018-11-22 10:34:58
- date last changed
- 2024-04-15 17:03:19
@article{1422d141-e9ab-4c11-9453-6332873ec724,
abstract = {{<p>Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, were studied. Carvone-positive and carvone-negative patients were compared regarding patch test data from baseline series and dental series. Dental series-tested carvone-positive patients were also compared with a matched group. A total of 147 out of 4,221 referred patients had a positive patch test to carvone. Sensitized patients had higher mean age and were primarily women; 73% had oral signs and 57% had oral lichen. Concomitant patch test reactions to gold, nickel and mercury were common. In the matched group-comparison carvone-positive patients had a higher frequency of oral lichen, but no difference was found in sensitization to gold and mercury.</p>}},
author = {{Kroona, Liv and Isaksson, Marléne and Ahlgren, Camilla and Dahlin, Jakob and Bruze, Magnus and Warfvinge, Gunnar}},
issn = {{1651-2057}},
keywords = {{l-carvoneCAS:6485-40-1; patchtest:allergens:contactallergy:orallichenplanus:orallichenoidlesions; spearmint}},
language = {{eng}},
month = {{11}},
number = {{10}},
pages = {{938--942}},
publisher = {{Medical Journals Limited}},
series = {{Acta Dermato-Venereologica}},
title = {{Carvone Contact Allergy in Southern Sweden : A 21-year Retrospective Study}},
url = {{http://dx.doi.org/10.2340/00015555-3009}},
doi = {{10.2340/00015555-3009}},
volume = {{98}},
year = {{2018}},
}