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Receptor binding mimetics: a novel molecularly imprinted polymer

Kempe, Maria LU and Mosbach, Klaus LU (1995) In Tetrahedron Letters 36(20). p.3563-3566
Abstract
A novel molecularly imprinted polymer was prepared by copolymerization of trimethylolpropane trimethacrylate (1) and methacrylic acid (3) in the presence of a dipeptide acting as the template. The recognition capability of the synthetic receptor-like binding sites produced in the polymer network for the peptide was demonstrated by using the polymer as a chiral stationary phase in HPLC. The polymer was superior to previously reported molecularly imprinted polymers in that unusually high racemic resolution and load capacity were demonstrated.
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Tetrahedron Letters
volume
36
issue
20
pages
3563 - 3566
publisher
Elsevier
external identifiers
  • scopus:0029024451
ISSN
0040-4039
DOI
10.1016/0040-4039(95)00559-U
language
English
LU publication?
yes
id
3b6fd1b7-a7ea-48bf-86a3-bff0008fe1a1 (old id 1516080)
date added to LUP
2016-04-01 15:31:32
date last changed
2021-01-03 03:41:58
@article{3b6fd1b7-a7ea-48bf-86a3-bff0008fe1a1,
  abstract     = {{A novel molecularly imprinted polymer was prepared by copolymerization of trimethylolpropane trimethacrylate (1) and methacrylic acid (3) in the presence of a dipeptide acting as the template. The recognition capability of the synthetic receptor-like binding sites produced in the polymer network for the peptide was demonstrated by using the polymer as a chiral stationary phase in HPLC. The polymer was superior to previously reported molecularly imprinted polymers in that unusually high racemic resolution and load capacity were demonstrated.}},
  author       = {{Kempe, Maria and Mosbach, Klaus}},
  issn         = {{0040-4039}},
  language     = {{eng}},
  number       = {{20}},
  pages        = {{3563--3566}},
  publisher    = {{Elsevier}},
  series       = {{Tetrahedron Letters}},
  title        = {{Receptor binding mimetics: a novel molecularly imprinted polymer}},
  url          = {{http://dx.doi.org/10.1016/0040-4039(95)00559-U}},
  doi          = {{10.1016/0040-4039(95)00559-U}},
  volume       = {{36}},
  year         = {{1995}},
}