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Synthesis of decaline analogues of isovelleral

Johansson, Martin H LU ; Aujard, I ; Röme, Daniel LU ; Anke, H and Sterner, Olov LU (2005) In Zeitschrift fuer Naturforschung. Section B: A Journal of Chemical Sciences 60(9). p.984-989
Abstract
Decaline analogues of the bioactive fungal sesquiterpene (+)-isovelleral (1a), retaining the bicyclo[4,1,0]hept-2-en-1,2-dicarbaldehyde system, were prepared, and their cytotoxic and antimicrobial activities were compared with those of the natural product. While the two isomers (+/-)-2 and (+/-)-3 were as active as isovelleral (1a), the isomer (+/-)-4 was approximately 10 times less potent.
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Zeitschrift fuer Naturforschung. Section B: A Journal of Chemical Sciences
volume
60
issue
9
pages
984 - 989
publisher
Verlag der Zeitschrift für Naturforschung
external identifiers
  • wos:000233452300013
  • scopus:27544508477
ISSN
0932-0776
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
id
c70cab15-58ec-465c-879d-441e1bbb598c (old id 152289)
alternative location
http://www.znaturforsch.com/ab/v60b/60b0984.pdf
http://www.znaturforsch.com/ab/v60b/c60b.htm#No9
date added to LUP
2016-04-01 15:20:23
date last changed
2022-01-28 04:54:07
@article{c70cab15-58ec-465c-879d-441e1bbb598c,
  abstract     = {{Decaline analogues of the bioactive fungal sesquiterpene (+)-isovelleral (1a), retaining the bicyclo[4,1,0]hept-2-en-1,2-dicarbaldehyde system, were prepared, and their cytotoxic and antimicrobial activities were compared with those of the natural product. While the two isomers (+/-)-2 and (+/-)-3 were as active as isovelleral (1a), the isomer (+/-)-4 was approximately 10 times less potent.}},
  author       = {{Johansson, Martin H and Aujard, I and Röme, Daniel and Anke, H and Sterner, Olov}},
  issn         = {{0932-0776}},
  language     = {{eng}},
  number       = {{9}},
  pages        = {{984--989}},
  publisher    = {{Verlag der Zeitschrift für Naturforschung}},
  series       = {{Zeitschrift fuer Naturforschung. Section B: A Journal of Chemical Sciences}},
  title        = {{Synthesis of decaline analogues of isovelleral}},
  url          = {{http://www.znaturforsch.com/ab/v60b/60b0984.pdf}},
  volume       = {{60}},
  year         = {{2005}},
}