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DNA compaction onto hydrophobic surfaces by different cationic surfactants

Cárdenas, Marité LU ; Nylander, Tommy LU ; Thomas, R K and Lindman, Björn LU (2005) In Langmuir 21(14). p.6495-6502
Abstract
DNA compaction by alkyltrimethylammonium surfactants at hydrophobized silica surfaces and the effect of the counterion, as well as the hydrocarbon chain length, was investigated by in situ null-ellipsometry. In addition, DNA compaction in the presence of a gemini surfactant, hexyl-alpha,omega-bis(dodecyldimethylammonium bromide), was studied. The type of cationic amphiphile used was found not to have a pronounced effect on the mixed DNA-cationic surfactant adsorbed layer thickness, although the surface concentration excess for the mixed layers seemed to follow the same trend as that for DNA-free surfactant layers. Interestingly, it was also found that the stability of the mixed adsorbed layer largely depends on the cationic surfactant used.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Langmuir
volume
21
issue
14
pages
6495 - 6502
publisher
The American Chemical Society (ACS)
external identifiers
  • wos:000230248500052
  • pmid:15982058
  • scopus:22444439152
ISSN
0743-7463
DOI
10.1021/la0501740
language
English
LU publication?
yes
id
f5bcc647-cfd6-4882-aa6e-1eea545c8f30 (old id 157259)
date added to LUP
2016-04-01 12:17:03
date last changed
2022-01-27 01:28:34
@article{f5bcc647-cfd6-4882-aa6e-1eea545c8f30,
  abstract     = {{DNA compaction by alkyltrimethylammonium surfactants at hydrophobized silica surfaces and the effect of the counterion, as well as the hydrocarbon chain length, was investigated by in situ null-ellipsometry. In addition, DNA compaction in the presence of a gemini surfactant, hexyl-alpha,omega-bis(dodecyldimethylammonium bromide), was studied. The type of cationic amphiphile used was found not to have a pronounced effect on the mixed DNA-cationic surfactant adsorbed layer thickness, although the surface concentration excess for the mixed layers seemed to follow the same trend as that for DNA-free surfactant layers. Interestingly, it was also found that the stability of the mixed adsorbed layer largely depends on the cationic surfactant used.}},
  author       = {{Cárdenas, Marité and Nylander, Tommy and Thomas, R K and Lindman, Björn}},
  issn         = {{0743-7463}},
  language     = {{eng}},
  number       = {{14}},
  pages        = {{6495--6502}},
  publisher    = {{The American Chemical Society (ACS)}},
  series       = {{Langmuir}},
  title        = {{DNA compaction onto hydrophobic surfaces by different cationic surfactants}},
  url          = {{http://dx.doi.org/10.1021/la0501740}},
  doi          = {{10.1021/la0501740}},
  volume       = {{21}},
  year         = {{2005}},
}