Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Monitoring and evaluation of malaria in pregnancy - developing a rational basis for control

Brabin, Bernard J. ; Warsame, Marian ; Uddenfeldt Wort, Ulrika LU ; Dellicour, Stephanie ; Hill, Jenny and Gies, Sabine (2008) In Malaria Journal 7(Suppl. 1).
Abstract
Monitoring and evaluation of malaria control in pregnancy is essential for assessing the efficacy and effectiveness of health interventions aimed at reducing the major burden of this disease on women living in endemic areas. Yet there is no currently integrated strategic approach on how this should be achieved. Malaria control in pregnancy is formulated in relation to epidemiological patterns of exposure. Current emphasis is on intermittent preventive treatment (IPTp) during pregnancy with sulphadoxine-pyrimethamine in higher transmission areas, combined with insecticide treated bed nets (ITNs) and case management. Emphasis in lower transmission areas is primarily on case management. This paper discusses a rational basis for monitoring and... (More)
Monitoring and evaluation of malaria control in pregnancy is essential for assessing the efficacy and effectiveness of health interventions aimed at reducing the major burden of this disease on women living in endemic areas. Yet there is no currently integrated strategic approach on how this should be achieved. Malaria control in pregnancy is formulated in relation to epidemiological patterns of exposure. Current emphasis is on intermittent preventive treatment (IPTp) during pregnancy with sulphadoxine-pyrimethamine in higher transmission areas, combined with insecticide treated bed nets (ITNs) and case management. Emphasis in lower transmission areas is primarily on case management. This paper discusses a rational basis for monitoring and evaluation based on: assessments of therapeutic and prophylactic drug efficacy; proportional reductions in parasite prevalence; seasonal effects; rapid assessment methodologies; birthweight and/or anaemia nomograms; case-coverage methods; maternal mortality indices; operational and programmatic indicators; and safety and pharmacovigilance of antimalarials in pregnancy. These approaches should be incorporated more effectively within National Programmes in order to facilitate surveillance and improve identification of high-risk women. Systems for utilizing routinely collected data should be strengthened, with greater attention to safety and pharmacovigilance with the advent of artemisinin combination therapies, and prospects of inadvertent exposures to artemisinins in the first trimester. Integrating monitoring activities within malaria control, reproductive health and adolescent-friendly services will be critical for implementation. Large-scale operational research is required to further evaluate the validity of currently proposed indicators, and in order to clarify the breadth and scale of implementation to be deployed. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Malaria Journal
volume
7
issue
Suppl. 1
publisher
BioMed Central (BMC)
external identifiers
  • wos:000278163700006
  • scopus:57649134566
  • pmid:19091040
ISSN
1475-2875
DOI
10.1186/1475-2875-7-S1-S6
language
English
LU publication?
yes
id
5b6ead0b-4b75-4448-a74d-c6f4598295b0 (old id 1616093)
alternative location
http://www.ncbi.nlm.nih.gov/sites/pubmed
date added to LUP
2016-04-01 13:41:28
date last changed
2022-01-27 20:31:46
@article{5b6ead0b-4b75-4448-a74d-c6f4598295b0,
  abstract     = {{Monitoring and evaluation of malaria control in pregnancy is essential for assessing the efficacy and effectiveness of health interventions aimed at reducing the major burden of this disease on women living in endemic areas. Yet there is no currently integrated strategic approach on how this should be achieved. Malaria control in pregnancy is formulated in relation to epidemiological patterns of exposure. Current emphasis is on intermittent preventive treatment (IPTp) during pregnancy with sulphadoxine-pyrimethamine in higher transmission areas, combined with insecticide treated bed nets (ITNs) and case management. Emphasis in lower transmission areas is primarily on case management. This paper discusses a rational basis for monitoring and evaluation based on: assessments of therapeutic and prophylactic drug efficacy; proportional reductions in parasite prevalence; seasonal effects; rapid assessment methodologies; birthweight and/or anaemia nomograms; case-coverage methods; maternal mortality indices; operational and programmatic indicators; and safety and pharmacovigilance of antimalarials in pregnancy. These approaches should be incorporated more effectively within National Programmes in order to facilitate surveillance and improve identification of high-risk women. Systems for utilizing routinely collected data should be strengthened, with greater attention to safety and pharmacovigilance with the advent of artemisinin combination therapies, and prospects of inadvertent exposures to artemisinins in the first trimester. Integrating monitoring activities within malaria control, reproductive health and adolescent-friendly services will be critical for implementation. Large-scale operational research is required to further evaluate the validity of currently proposed indicators, and in order to clarify the breadth and scale of implementation to be deployed.}},
  author       = {{Brabin, Bernard J. and Warsame, Marian and Uddenfeldt Wort, Ulrika and Dellicour, Stephanie and Hill, Jenny and Gies, Sabine}},
  issn         = {{1475-2875}},
  language     = {{eng}},
  number       = {{Suppl. 1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{Malaria Journal}},
  title        = {{Monitoring and evaluation of malaria in pregnancy - developing a rational basis for control}},
  url          = {{http://dx.doi.org/10.1186/1475-2875-7-S1-S6}},
  doi          = {{10.1186/1475-2875-7-S1-S6}},
  volume       = {{7}},
  year         = {{2008}},
}