Should we Refrain from Performing Oophorectomy in Conjunction with Radical Cystectomy for Bladder Cancer?
(2017) In European Urology 71(6). p.851-853- Abstract
Radical cystectomy with neoadjuvant chemotherapy is the gold standard for treating muscle-invasive bladder cancer. Women subjected to radical cystectomy are frequently postmenopausal, and the median age for bladder cancer diagnosis in women in Sweden is currently 73 yr (Swedish National Bladder Cancer Register). Traditionally, most women treated with radical cystectomy have undergone simultaneous bilateral oophorectomy and hysterosalpingectomy to diminish the risk of later ovarian disease and ovarian bladder cancer recurrence, but also the belief that there is no impact on health or health-related quality of life associated with oophorectomy and the fact that it might be easier surgery to take the ovarian pedicles, rather than sparing... (More)
Radical cystectomy with neoadjuvant chemotherapy is the gold standard for treating muscle-invasive bladder cancer. Women subjected to radical cystectomy are frequently postmenopausal, and the median age for bladder cancer diagnosis in women in Sweden is currently 73 yr (Swedish National Bladder Cancer Register). Traditionally, most women treated with radical cystectomy have undergone simultaneous bilateral oophorectomy and hysterosalpingectomy to diminish the risk of later ovarian disease and ovarian bladder cancer recurrence, but also the belief that there is no impact on health or health-related quality of life associated with oophorectomy and the fact that it might be easier surgery to take the ovarian pedicles, rather than sparing the ovaries. However, pelvic organ preservation is considered in some younger women to diminish postoperative functional impairment. Based on recent literature in several areas related to oophorectomy, we question the rationale and arguments for performing oophorectomy in women in conjunction with radical cystectomy for bladder cancer. It can be questioned whether routine bilateral oophorectomy during radical cystectomy is advisable in premenopausal women, and the same might also apply to selected postmenopausal women.
(Less)
- author
- Liedberg, Fredrik LU ; Jancke, Georg LU ; Sörenby, Anne and Kannisto, Päivi LU
- organization
- publishing date
- 2017
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bladder cancer, Ovary, Radical cystectomy
- in
- European Urology
- volume
- 71
- issue
- 6
- pages
- 851 - 853
- publisher
- Elsevier
- external identifiers
-
- pmid:27771127
- wos:000400050300009
- scopus:85008957402
- ISSN
- 0302-2838
- DOI
- 10.1016/j.eururo.2016.10.010
- language
- English
- LU publication?
- yes
- id
- 1654b1af-cb1e-4324-afa8-1953cf63a873
- date added to LUP
- 2017-02-10 12:59:41
- date last changed
- 2024-04-14 03:58:00
@article{1654b1af-cb1e-4324-afa8-1953cf63a873,
abstract = {{<p>Radical cystectomy with neoadjuvant chemotherapy is the gold standard for treating muscle-invasive bladder cancer. Women subjected to radical cystectomy are frequently postmenopausal, and the median age for bladder cancer diagnosis in women in Sweden is currently 73 yr (Swedish National Bladder Cancer Register). Traditionally, most women treated with radical cystectomy have undergone simultaneous bilateral oophorectomy and hysterosalpingectomy to diminish the risk of later ovarian disease and ovarian bladder cancer recurrence, but also the belief that there is no impact on health or health-related quality of life associated with oophorectomy and the fact that it might be easier surgery to take the ovarian pedicles, rather than sparing the ovaries. However, pelvic organ preservation is considered in some younger women to diminish postoperative functional impairment. Based on recent literature in several areas related to oophorectomy, we question the rationale and arguments for performing oophorectomy in women in conjunction with radical cystectomy for bladder cancer. It can be questioned whether routine bilateral oophorectomy during radical cystectomy is advisable in premenopausal women, and the same might also apply to selected postmenopausal women.</p>}},
author = {{Liedberg, Fredrik and Jancke, Georg and Sörenby, Anne and Kannisto, Päivi}},
issn = {{0302-2838}},
keywords = {{Bladder cancer; Ovary; Radical cystectomy}},
language = {{eng}},
number = {{6}},
pages = {{851--853}},
publisher = {{Elsevier}},
series = {{European Urology}},
title = {{Should we Refrain from Performing Oophorectomy in Conjunction with Radical Cystectomy for Bladder Cancer?}},
url = {{http://dx.doi.org/10.1016/j.eururo.2016.10.010}},
doi = {{10.1016/j.eururo.2016.10.010}},
volume = {{71}},
year = {{2017}},
}