Extensive acute deep vein thrombosis of the iliocaval segment: midterm results of thrombolysis and stent placement.
(2007) In Journal of Vascular and Interventional Radiology 18(2). p.243-250- Abstract
- PURPOSE: To evaluate patency and clinical outcome in patients treated with catheter-directed thrombolysis and stent placement for acute extensive thrombosis affecting the iliocaval segment. MATERIALS AND METHODS: During a 10-year period (1994-2005), 37 patients with 44 limbs (26 female, median age 31 years) with acute extensive venous thrombosis affecting the iliocaval segment were treated with catheter-directed thrombolysis. Angioplasty and stent placement was performed in 36 limbs (82%) for underlying stenosis or residual thrombosis. A prospectively registered database was analyzed in combination with a telephone interview about clinical symptoms. RESULTS: Technical success was achieved in all 44 limbs and clinical success in 42 of 44... (More)
- PURPOSE: To evaluate patency and clinical outcome in patients treated with catheter-directed thrombolysis and stent placement for acute extensive thrombosis affecting the iliocaval segment. MATERIALS AND METHODS: During a 10-year period (1994-2005), 37 patients with 44 limbs (26 female, median age 31 years) with acute extensive venous thrombosis affecting the iliocaval segment were treated with catheter-directed thrombolysis. Angioplasty and stent placement was performed in 36 limbs (82%) for underlying stenosis or residual thrombosis. A prospectively registered database was analyzed in combination with a telephone interview about clinical symptoms. RESULTS: Technical success was achieved in all 44 limbs and clinical success in 42 of 44 (96%) limbs. Primary patency after a median imaging follow-up interval of 16 months was 34 of 44 (77%) limbs, assisted primary patency was 38 of 44 (86%) limbs, and secondary patency was 39 of 44 (89%) limbs. Thirty of 44 (68%) limbs were asymptomatic after a median clinical follow-up of 27 months, eight (18%) limbs were moderately improved, two (5%) limbs were unchanged, two (5%) limbs were moderately worse, and two (5%) limbs had no clinical follow-up. Complications occurred in six (16%) patients, three (8%) of which were major complications. No patient developed symptomatic pulmonary embolism. CONCLUSIONS: Catheter-directed thrombolysis and stent placement is a safe and effective treatment for acute iliocaval thrombosis. Clinical midterm results are encouraging. Thrombolyzed and stented segments remain patent in the vast majority of patients after 16 months. Primary and aggressive stent placement in the iliocaval vein segments can prevent rethrombosis and ensure patency. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/166985
- author
- Kölbel, Tilo LU ; Lindh, Mats LU ; Holst, Jan LU ; Uher, Petr LU ; Eriksson, Karl-Fredrik LU ; Sonesson, Björn LU ; Malina, Martin LU and Ivancev, Krasnodar
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Vascular and Interventional Radiology
- volume
- 18
- issue
- 2
- pages
- 243 - 250
- publisher
- Society of Interventional Radiology
- external identifiers
-
- wos:000244736200009
- scopus:34247265939
- ISSN
- 1051-0443
- DOI
- 10.1016/j.jvir.2006.12.002
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Unit for Clinical Vascular Disease Research (013242410), Emergency medicine/Medicine/Surgery (013240200), Medical Radiology Unit (013241410)
- id
- f691085c-ec64-4990-966d-ae2c5e4d2cef (old id 166985)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17327557&dopt=Abstract
- date added to LUP
- 2016-04-01 15:47:28
- date last changed
- 2022-02-27 08:46:13
@article{f691085c-ec64-4990-966d-ae2c5e4d2cef,
abstract = {{PURPOSE: To evaluate patency and clinical outcome in patients treated with catheter-directed thrombolysis and stent placement for acute extensive thrombosis affecting the iliocaval segment. MATERIALS AND METHODS: During a 10-year period (1994-2005), 37 patients with 44 limbs (26 female, median age 31 years) with acute extensive venous thrombosis affecting the iliocaval segment were treated with catheter-directed thrombolysis. Angioplasty and stent placement was performed in 36 limbs (82%) for underlying stenosis or residual thrombosis. A prospectively registered database was analyzed in combination with a telephone interview about clinical symptoms. RESULTS: Technical success was achieved in all 44 limbs and clinical success in 42 of 44 (96%) limbs. Primary patency after a median imaging follow-up interval of 16 months was 34 of 44 (77%) limbs, assisted primary patency was 38 of 44 (86%) limbs, and secondary patency was 39 of 44 (89%) limbs. Thirty of 44 (68%) limbs were asymptomatic after a median clinical follow-up of 27 months, eight (18%) limbs were moderately improved, two (5%) limbs were unchanged, two (5%) limbs were moderately worse, and two (5%) limbs had no clinical follow-up. Complications occurred in six (16%) patients, three (8%) of which were major complications. No patient developed symptomatic pulmonary embolism. CONCLUSIONS: Catheter-directed thrombolysis and stent placement is a safe and effective treatment for acute iliocaval thrombosis. Clinical midterm results are encouraging. Thrombolyzed and stented segments remain patent in the vast majority of patients after 16 months. Primary and aggressive stent placement in the iliocaval vein segments can prevent rethrombosis and ensure patency.}},
author = {{Kölbel, Tilo and Lindh, Mats and Holst, Jan and Uher, Petr and Eriksson, Karl-Fredrik and Sonesson, Björn and Malina, Martin and Ivancev, Krasnodar}},
issn = {{1051-0443}},
language = {{eng}},
number = {{2}},
pages = {{243--250}},
publisher = {{Society of Interventional Radiology}},
series = {{Journal of Vascular and Interventional Radiology}},
title = {{Extensive acute deep vein thrombosis of the iliocaval segment: midterm results of thrombolysis and stent placement.}},
url = {{http://dx.doi.org/10.1016/j.jvir.2006.12.002}},
doi = {{10.1016/j.jvir.2006.12.002}},
volume = {{18}},
year = {{2007}},
}