Increased Echolucency of Carotid Plaques in Patients With Type 2 Diabetes.
Östling, Gerd LU ; Hedblad, Bo LU ; Berglund, Göran LU and Goncalves, Isabel LU
(2007)
In Stroke: a journal of cerebral circulation
38.
p.2074-2078
- Abstract
- Background and Purpose - Diabetes is associated with the presence of moderate to large atherosclerotic carotid plaques. Previous carotid ultrasound studies have associated plaques with low echogenicity with a higher risk of cerebrovascular events. The aim of this study was to evaluate whether patients with type 2 diabetes have different plaque echogenicity than do nondiabetic subjects. Methods - Forty-seven type 2 diabetic and 51 nondiabetic subjects with a carotid plaque in the right artery were included in this study. All patients were born in 1935 to 1936 and were participants in a population-based study. Carotid ultrasonography was performed and the risk factors for cardiovascular disease were determined. Plaque echogenicity was... (More)
- Background and Purpose - Diabetes is associated with the presence of moderate to large atherosclerotic carotid plaques. Previous carotid ultrasound studies have associated plaques with low echogenicity with a higher risk of cerebrovascular events. The aim of this study was to evaluate whether patients with type 2 diabetes have different plaque echogenicity than do nondiabetic subjects. Methods - Forty-seven type 2 diabetic and 51 nondiabetic subjects with a carotid plaque in the right artery were included in this study. All patients were born in 1935 to 1936 and were participants in a population-based study. Carotid ultrasonography was performed and the risk factors for cardiovascular disease were determined. Plaque echogenicity was assessed quantitatively on B-mode ultrasound images by standardized gray-scale median values. Results - Gray-scale median values were significantly lower, indicating more echolucent plaques, in patients with type 2 diabetes compared with nondiabetics (37.0 +/- 14.8 vs 45.5 +/- 15.4, P=0.007). Of the other risk factors studied, only triglycerides were significantly associated with the echogenicity of the plaque. Conclusions - Patients with type 2 diabetes have more echolucent plaques compared with nondiabetic subjects. This might be associated with the higher risk of cardiovascular events among diabetics. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/168084
- author
- Östling, Gerd
LU
; Hedblad, Bo
LU
; Berglund, Göran
LU
and Goncalves, Isabel
LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Stroke: a journal of cerebral circulation
- volume
- 38
- pages
- 2074 - 2078
- publisher
- American Heart Association
- external identifiers
-
- wos:000247513300029
- scopus:34347328234
- ISSN
- 1524-4628
- DOI
- 10.1161/STROKEAHA.106.480830
- language
- English
- LU publication?
- yes
- id
- f70e3cac-9698-45c0-8c8d-643063a6dc61 (old id 168084)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17525393&dopt=Abstract
- date added to LUP
- 2016-04-01 15:43:29
- date last changed
- 2022-02-07 11:24:13
@article{f70e3cac-9698-45c0-8c8d-643063a6dc61,
abstract = {{Background and Purpose - Diabetes is associated with the presence of moderate to large atherosclerotic carotid plaques. Previous carotid ultrasound studies have associated plaques with low echogenicity with a higher risk of cerebrovascular events. The aim of this study was to evaluate whether patients with type 2 diabetes have different plaque echogenicity than do nondiabetic subjects. Methods - Forty-seven type 2 diabetic and 51 nondiabetic subjects with a carotid plaque in the right artery were included in this study. All patients were born in 1935 to 1936 and were participants in a population-based study. Carotid ultrasonography was performed and the risk factors for cardiovascular disease were determined. Plaque echogenicity was assessed quantitatively on B-mode ultrasound images by standardized gray-scale median values. Results - Gray-scale median values were significantly lower, indicating more echolucent plaques, in patients with type 2 diabetes compared with nondiabetics (37.0 +/- 14.8 vs 45.5 +/- 15.4, P=0.007). Of the other risk factors studied, only triglycerides were significantly associated with the echogenicity of the plaque. Conclusions - Patients with type 2 diabetes have more echolucent plaques compared with nondiabetic subjects. This might be associated with the higher risk of cardiovascular events among diabetics.}},
author = {{Östling, Gerd and Hedblad, Bo and Berglund, Göran and Goncalves, Isabel}},
issn = {{1524-4628}},
language = {{eng}},
pages = {{2074--2078}},
publisher = {{American Heart Association}},
series = {{Stroke: a journal of cerebral circulation}},
title = {{Increased Echolucency of Carotid Plaques in Patients With Type 2 Diabetes.}},
url = {{http://dx.doi.org/10.1161/STROKEAHA.106.480830}},
doi = {{10.1161/STROKEAHA.106.480830}},
volume = {{38}},
year = {{2007}},
}