Cerebellar molecular layer interneurons - computational properties and roles in learning.
(2010) In Trends in Neurosciences 33. p.524-532- Abstract
- In recent years there has been an increased interest in the function of inhibitory interneurons. In the cerebellum this interest has been paired with successes in obtaining recordings from these neurons in vivo and genetic manipulations to probe their function during behavioral tasks such as motor learning. This review focuses on a synthesis of recent findings on the computational properties that these neurons confer to the cerebellar circuitry and on their recently discovered capacity for plasticity and learning in vivo. Since the circuitry of the cerebellar cortex is relatively well-defined, the specificity with which the potential roles of these interneurons can be described will help to guide new avenues of research on the functions of... (More)
- In recent years there has been an increased interest in the function of inhibitory interneurons. In the cerebellum this interest has been paired with successes in obtaining recordings from these neurons in vivo and genetic manipulations to probe their function during behavioral tasks such as motor learning. This review focuses on a synthesis of recent findings on the computational properties that these neurons confer to the cerebellar circuitry and on their recently discovered capacity for plasticity and learning in vivo. Since the circuitry of the cerebellar cortex is relatively well-defined, the specificity with which the potential roles of these interneurons can be described will help to guide new avenues of research on the functions of interneurons in general. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1687814
- author
- Jörntell, Henrik LU ; Bengtsson, Fredrik LU ; Schonewille, Martijn and De Zeeuw, Chris I
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Trends in Neurosciences
- volume
- 33
- pages
- 524 - 532
- publisher
- Elsevier
- external identifiers
-
- wos:000284493700005
- pmid:20869126
- scopus:77958155395
- pmid:20869126
- ISSN
- 1878-108X
- DOI
- 10.1016/j.tins.2010.08.004
- language
- English
- LU publication?
- yes
- id
- a85bb391-3b7d-4d6c-ba2e-f7726e3ada73 (old id 1687814)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/20869126?dopt=Abstract
- date added to LUP
- 2016-04-04 09:15:33
- date last changed
- 2023-11-15 13:45:20
@article{a85bb391-3b7d-4d6c-ba2e-f7726e3ada73,
abstract = {{In recent years there has been an increased interest in the function of inhibitory interneurons. In the cerebellum this interest has been paired with successes in obtaining recordings from these neurons in vivo and genetic manipulations to probe their function during behavioral tasks such as motor learning. This review focuses on a synthesis of recent findings on the computational properties that these neurons confer to the cerebellar circuitry and on their recently discovered capacity for plasticity and learning in vivo. Since the circuitry of the cerebellar cortex is relatively well-defined, the specificity with which the potential roles of these interneurons can be described will help to guide new avenues of research on the functions of interneurons in general.}},
author = {{Jörntell, Henrik and Bengtsson, Fredrik and Schonewille, Martijn and De Zeeuw, Chris I}},
issn = {{1878-108X}},
language = {{eng}},
pages = {{524--532}},
publisher = {{Elsevier}},
series = {{Trends in Neurosciences}},
title = {{Cerebellar molecular layer interneurons - computational properties and roles in learning.}},
url = {{http://dx.doi.org/10.1016/j.tins.2010.08.004}},
doi = {{10.1016/j.tins.2010.08.004}},
volume = {{33}},
year = {{2010}},
}