Metabolic syndrome and psychiatrists' choice of follow-up interventions in patients treated with atypical antipsychotics in Denmark and Sweden
(2011) In Nordic Journal of Psychiatry 65(1). p.40-46- Abstract
- Introduction: The aim of the present study was to obtain point prevalence estimates of the metabolic syndrome according to the NCEP III criteria in a sample of patients with schizophrenia spectrum disorders treated with atypical antipsychotic drugs in Denmark and Sweden, and to assess the psychiatrists' choice of recommendations for follow-up interventions based on the patients' laboratory results. Method: This was a cross-sectional, observational multi-center study in Denmark and Sweden, in consecutively screened in- and outpatients with schizophrenia spectrum disorders and continuously treated for at least 3 months with atypical antipsychotic drugs. Results: The metabolic syndrome as per medical history was present in 1% of 582 evaluable... (More)
- Introduction: The aim of the present study was to obtain point prevalence estimates of the metabolic syndrome according to the NCEP III criteria in a sample of patients with schizophrenia spectrum disorders treated with atypical antipsychotic drugs in Denmark and Sweden, and to assess the psychiatrists' choice of recommendations for follow-up interventions based on the patients' laboratory results. Method: This was a cross-sectional, observational multi-center study in Denmark and Sweden, in consecutively screened in- and outpatients with schizophrenia spectrum disorders and continuously treated for at least 3 months with atypical antipsychotic drugs. Results: The metabolic syndrome as per medical history was present in 1% of 582 evaluable patients at baseline. After performing laboratory measurements and applying the NCEP III criteria, metabolic syndrome was confirmed in 43% of subjects. The high rate of metabolic syndrome did not elicit much decisive action on the part of the treating psychiatrists; the most frequent action taken was dietary and exercise advice (in 75% of subjects), while in 54% and 19% of subjects a laboratory follow-up and blood pressure follow-up were advised respectively. Change of antipsychotic medication was recommended in only 10% of patients, and in further 11% of patients, no action was taken. Conclusion: Observed metabolic syndrome prevalence rates were at least twice the rates observed in a normal, non-diabetic population. It appears that in this vulnerable population of patients with schizophrenia spectrum disorders, metabolic syndrome remains underdiagnosed and undertreated. (Less)
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https://lup.lub.lu.se/record/1868940
- author
- Larsen, John Teilmann ; Fagerquist, Maria ; Holdrup, Mette ; Christensen, Bjarne ; Sigalin, Catarina and Nilsson, Peter LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Interventions, Metabolic syndrome, Prevalence, Schizophrenia
- in
- Nordic Journal of Psychiatry
- volume
- 65
- issue
- 1
- pages
- 40 - 46
- publisher
- Informa Healthcare
- external identifiers
-
- wos:000286683100008
- scopus:78751519432
- pmid:20482460
- ISSN
- 1502-4725
- DOI
- 10.3109/08039488.2010.486443
- language
- English
- LU publication?
- yes
- id
- 8df2e301-058f-4846-b29b-63de5dfe95ae (old id 1868940)
- date added to LUP
- 2016-04-01 09:48:23
- date last changed
- 2022-03-19 06:29:17
@article{8df2e301-058f-4846-b29b-63de5dfe95ae,
abstract = {{Introduction: The aim of the present study was to obtain point prevalence estimates of the metabolic syndrome according to the NCEP III criteria in a sample of patients with schizophrenia spectrum disorders treated with atypical antipsychotic drugs in Denmark and Sweden, and to assess the psychiatrists' choice of recommendations for follow-up interventions based on the patients' laboratory results. Method: This was a cross-sectional, observational multi-center study in Denmark and Sweden, in consecutively screened in- and outpatients with schizophrenia spectrum disorders and continuously treated for at least 3 months with atypical antipsychotic drugs. Results: The metabolic syndrome as per medical history was present in 1% of 582 evaluable patients at baseline. After performing laboratory measurements and applying the NCEP III criteria, metabolic syndrome was confirmed in 43% of subjects. The high rate of metabolic syndrome did not elicit much decisive action on the part of the treating psychiatrists; the most frequent action taken was dietary and exercise advice (in 75% of subjects), while in 54% and 19% of subjects a laboratory follow-up and blood pressure follow-up were advised respectively. Change of antipsychotic medication was recommended in only 10% of patients, and in further 11% of patients, no action was taken. Conclusion: Observed metabolic syndrome prevalence rates were at least twice the rates observed in a normal, non-diabetic population. It appears that in this vulnerable population of patients with schizophrenia spectrum disorders, metabolic syndrome remains underdiagnosed and undertreated.}},
author = {{Larsen, John Teilmann and Fagerquist, Maria and Holdrup, Mette and Christensen, Bjarne and Sigalin, Catarina and Nilsson, Peter}},
issn = {{1502-4725}},
keywords = {{Interventions; Metabolic syndrome; Prevalence; Schizophrenia}},
language = {{eng}},
number = {{1}},
pages = {{40--46}},
publisher = {{Informa Healthcare}},
series = {{Nordic Journal of Psychiatry}},
title = {{Metabolic syndrome and psychiatrists' choice of follow-up interventions in patients treated with atypical antipsychotics in Denmark and Sweden}},
url = {{http://dx.doi.org/10.3109/08039488.2010.486443}},
doi = {{10.3109/08039488.2010.486443}},
volume = {{65}},
year = {{2011}},
}