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Health-related quality of life is impaired in active collagenous colitis

Hjortswang, Henrik ; Tysk, Curt ; Bohr, Johan ; Benoni, Cecilia LU ; Vigren, Lina LU ; Kilander, Anders ; Larsson, Lasse ; Taha, Yesuf and Strom, Magnus (2011) In Digestive and Liver Disease 43(2). p.102-109
Abstract
Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL survey, 116 patients with collagenous colitis at four Swedish hospitals completed four health-related quality of life questionnaires, two disease-specific (Inflammatory Bowel Disease Questionnaire and Rating Form of IBD Patient Concerns), and two generic (Short Form 36, SF-36, and Psychological General Well-Being, PGWB), and a one-week symptom... (More)
Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL survey, 116 patients with collagenous colitis at four Swedish hospitals completed four health-related quality of life questionnaires, two disease-specific (Inflammatory Bowel Disease Questionnaire and Rating Form of IBD Patient Concerns), and two generic (Short Form 36, SF-36, and Psychological General Well-Being, PGWB), and a one-week symptom diary. Demographic and disease-related data were collected. Results for the collagenous colitis population were compared with a background population controlled for age and gender (n = 8931). Results: Compared with a Swedish background population, patients with collagenous colitis scored significantly worse in all Short Form 36 dimensions (p < 0.01), except physical function. Patients with active disease scored worse health-related quality of life than patients in remission. Co-existing disease had an impact on health-related quality of life measured with the generic measures. Lower education level and shorter disease duration were associated with decreased well-being. Conclusion: Health-related quality of life was impaired in patients with collagenous colitis compared with a background population. Disease activity is the most important factor associated with impairment of health-related quality of life. Patients in remission have a health-related quality of life similar to a background population. (C) 2010 Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l. (Less)
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author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Collagenous colitis, Health, Health-related quality of life, Inflammatory bowel disease (IBD), Microscopic colitis, Quality of life
in
Digestive and Liver Disease
volume
43
issue
2
pages
102 - 109
publisher
Elsevier
external identifiers
  • wos:000290008100004
  • scopus:78651413985
  • pmid:20638918
ISSN
1590-8658
DOI
10.1016/j.dld.2010.06.004
language
English
LU publication?
yes
id
d52213eb-72db-4934-a66c-6daeaceaa14d (old id 1964516)
date added to LUP
2016-04-01 10:59:12
date last changed
2022-01-26 04:31:17
@article{d52213eb-72db-4934-a66c-6daeaceaa14d,
  abstract     = {{Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL survey, 116 patients with collagenous colitis at four Swedish hospitals completed four health-related quality of life questionnaires, two disease-specific (Inflammatory Bowel Disease Questionnaire and Rating Form of IBD Patient Concerns), and two generic (Short Form 36, SF-36, and Psychological General Well-Being, PGWB), and a one-week symptom diary. Demographic and disease-related data were collected. Results for the collagenous colitis population were compared with a background population controlled for age and gender (n = 8931). Results: Compared with a Swedish background population, patients with collagenous colitis scored significantly worse in all Short Form 36 dimensions (p &lt; 0.01), except physical function. Patients with active disease scored worse health-related quality of life than patients in remission. Co-existing disease had an impact on health-related quality of life measured with the generic measures. Lower education level and shorter disease duration were associated with decreased well-being. Conclusion: Health-related quality of life was impaired in patients with collagenous colitis compared with a background population. Disease activity is the most important factor associated with impairment of health-related quality of life. Patients in remission have a health-related quality of life similar to a background population. (C) 2010 Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.}},
  author       = {{Hjortswang, Henrik and Tysk, Curt and Bohr, Johan and Benoni, Cecilia and Vigren, Lina and Kilander, Anders and Larsson, Lasse and Taha, Yesuf and Strom, Magnus}},
  issn         = {{1590-8658}},
  keywords     = {{Collagenous colitis; Health; Health-related quality of life; Inflammatory bowel disease (IBD); Microscopic colitis; Quality of life}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{102--109}},
  publisher    = {{Elsevier}},
  series       = {{Digestive and Liver Disease}},
  title        = {{Health-related quality of life is impaired in active collagenous colitis}},
  url          = {{http://dx.doi.org/10.1016/j.dld.2010.06.004}},
  doi          = {{10.1016/j.dld.2010.06.004}},
  volume       = {{43}},
  year         = {{2011}},
}