Cartilage mechanics and morphology, synovitis and proteoglycan fragments in rabbit joint fluid after prosthetic meniscal substitution
Messner, Karola ; Lohmander, L. Stefan LU
and Gillquist, Jan
(1993)
In Biomaterials
14(3).
p.163-168
- Abstract
The effects of meniscal substitution with a Dacron® or Teflon® prosthesis on rabbit knee-joint cartilage were studied by indentation tests, gross and histological inspection, analysis of proteoglycan fragments in joint fluid and an evaluation of synovial changes. Cartilage mechanics and cartilage morphology were similarly abnormal after meniscectomy and meniscal substitution. The elevated concentrations of proteoglycan fragments in joint fluid and the more severe synovial changes in joints with a meniscal substitute, as compared to meniscectomy, probably resulted from irritation of the artificial implant, but also reflected the remaining effects from the necessary bone drilling. In this short-term experiment, the use of an artificial... (More)
The effects of meniscal substitution with a Dacron® or Teflon® prosthesis on rabbit knee-joint cartilage were studied by indentation tests, gross and histological inspection, analysis of proteoglycan fragments in joint fluid and an evaluation of synovial changes. Cartilage mechanics and cartilage morphology were similarly abnormal after meniscectomy and meniscal substitution. The elevated concentrations of proteoglycan fragments in joint fluid and the more severe synovial changes in joints with a meniscal substitute, as compared to meniscectomy, probably resulted from irritation of the artificial implant, but also reflected the remaining effects from the necessary bone drilling. In this short-term experiment, the use of an artificial meniscal substitute could not prevent cartilage degeneration after meniscectomy.
(Less)
- author
- Messner, Karola
; Lohmander, L. Stefan
LU
and Gillquist, Jan
- organization
- publishing date
- 1993
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Dacron®, Knee-joint prosthesis, meniscectomy, proteoglycan, synovitis, Teflon®
- in
- Biomaterials
- volume
- 14
- issue
- 3
- pages
- 6 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:0027551632
- pmid:8476988
- ISSN
- 0142-9612
- DOI
- 10.1016/0142-9612(93)90018-W
- language
- English
- LU publication?
- yes
- id
- 21dac920-10b7-45cd-86d9-266c433489c5
- date added to LUP
- 2016-05-04 18:31:22
- date last changed
- 2024-02-18 17:10:30
@article{21dac920-10b7-45cd-86d9-266c433489c5,
abstract = {{<p>The effects of meniscal substitution with a Dacron® or Teflon® prosthesis on rabbit knee-joint cartilage were studied by indentation tests, gross and histological inspection, analysis of proteoglycan fragments in joint fluid and an evaluation of synovial changes. Cartilage mechanics and cartilage morphology were similarly abnormal after meniscectomy and meniscal substitution. The elevated concentrations of proteoglycan fragments in joint fluid and the more severe synovial changes in joints with a meniscal substitute, as compared to meniscectomy, probably resulted from irritation of the artificial implant, but also reflected the remaining effects from the necessary bone drilling. In this short-term experiment, the use of an artificial meniscal substitute could not prevent cartilage degeneration after meniscectomy.</p>}},
author = {{Messner, Karola and Lohmander, L. Stefan and Gillquist, Jan}},
issn = {{0142-9612}},
keywords = {{Dacron®; Knee-joint prosthesis; meniscectomy; proteoglycan; synovitis; Teflon®}},
language = {{eng}},
number = {{3}},
pages = {{163--168}},
publisher = {{Elsevier}},
series = {{Biomaterials}},
title = {{Cartilage mechanics and morphology, synovitis and proteoglycan fragments in rabbit joint fluid after prosthetic meniscal substitution}},
url = {{http://dx.doi.org/10.1016/0142-9612(93)90018-W}},
doi = {{10.1016/0142-9612(93)90018-W}},
volume = {{14}},
year = {{1993}},
}