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Alternative methods providing enhanced sensitivity and selectivity in capillary electroseparation experiments

Schweitz, L ; Petersson, M ; Johansson, Thomas LU and Nilsson, S (2000) In Journal of Chromatography A 892(1-2). p.203-217
Abstract
The study of alternative and novel techniques for altering selectivity and enhancing sensitivity as well as injection and detection protocols are important in the ongoing development of capillary electroseparation protocols. Some recent research from our laboratory in these fields is presented and discussed in this review. To improve sensitivity an off-line sample enrichment technique utilising solvent evaporation in a levitated drop or an on-line solid-phase extraction protocol was used. The selectivity was tuned by the use of protein gels or molecularly imprinted polymer mediated capillary electrochromatography. Furthermore, a picolitre droplet injection method is described as well as a detection protocol based on laser-induced... (More)
The study of alternative and novel techniques for altering selectivity and enhancing sensitivity as well as injection and detection protocols are important in the ongoing development of capillary electroseparation protocols. Some recent research from our laboratory in these fields is presented and discussed in this review. To improve sensitivity an off-line sample enrichment technique utilising solvent evaporation in a levitated drop or an on-line solid-phase extraction protocol was used. The selectivity was tuned by the use of protein gels or molecularly imprinted polymer mediated capillary electrochromatography. Furthermore, a picolitre droplet injection method is described as well as a detection protocol based on laser-induced fluorescence imaging. (C) 2000 Elsevier Science B.V, All rights reserved. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Chromatography A
volume
892
issue
1-2
pages
203 - 217
publisher
Elsevier
external identifiers
  • scopus:0034665526
ISSN
0021-9673
DOI
10.1016/S0021-9673(00)00239-9
language
English
LU publication?
yes
id
2e2086e2-5348-4855-985f-2f5e5ca5b4bc (old id 2259339)
date added to LUP
2016-04-04 09:28:22
date last changed
2022-01-29 18:00:14
@article{2e2086e2-5348-4855-985f-2f5e5ca5b4bc,
  abstract     = {{The study of alternative and novel techniques for altering selectivity and enhancing sensitivity as well as injection and detection protocols are important in the ongoing development of capillary electroseparation protocols. Some recent research from our laboratory in these fields is presented and discussed in this review. To improve sensitivity an off-line sample enrichment technique utilising solvent evaporation in a levitated drop or an on-line solid-phase extraction protocol was used. The selectivity was tuned by the use of protein gels or molecularly imprinted polymer mediated capillary electrochromatography. Furthermore, a picolitre droplet injection method is described as well as a detection protocol based on laser-induced fluorescence imaging. (C) 2000 Elsevier Science B.V, All rights reserved.}},
  author       = {{Schweitz, L and Petersson, M and Johansson, Thomas and Nilsson, S}},
  issn         = {{0021-9673}},
  language     = {{eng}},
  number       = {{1-2}},
  pages        = {{203--217}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Chromatography A}},
  title        = {{Alternative methods providing enhanced sensitivity and selectivity in capillary electroseparation experiments}},
  url          = {{https://lup.lub.lu.se/search/files/5333660/2297566.pdf}},
  doi          = {{10.1016/S0021-9673(00)00239-9}},
  volume       = {{892}},
  year         = {{2000}},
}