Echocardiographic prediction of patent ductus arteriosus in need of therapeutic intervention
Harling, S. ; Pupp, Ingrid LU
; Baigi, A.
and Pesonen, E.
(2011)
In Acta Pædiatrica
100(2).
p.231-235
- Abstract
- Aim: To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment. Methods: Forty-five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24 +/- 6 and 72 +/- 6 h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA/Ao) ratio and Doppler pixels representing ductal shunting. Results: Twenty-eight infants had a PDA with a detectable left-to-right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a... (More)
- Aim: To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment. Methods: Forty-five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24 +/- 6 and 72 +/- 6 h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA/Ao) ratio and Doppler pixels representing ductal shunting. Results: Twenty-eight infants had a PDA with a detectable left-to-right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a sensitivity of 89%, a specificity of 70%, a positive likelihood ratio of 2.97 and a negative likelihood ratio of 0.16 at the age of 72 h. The efficacy of the method at 72 h of age was 84%. The corresponding efficacy of the pulsatile Doppler curve was 72%, percentage of green colour pixels 63% and the LA/Ao ratio 53%. Conclusion: Ductus diameter appears to be the most important variable in determining the need for therapeutic intervention for PDA in preterm infants. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2295900
- author
- Harling, S.
; Pupp, Ingrid
LU
; Baigi, A.
and Pesonen, E.
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Colour Doppler echocardiography, Patent ductus arteriosus, Prediction, Very low birthweight infant
- in
- Acta Pædiatrica
- volume
- 100
- issue
- 2
- pages
- 231 - 235
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000285971100016
- scopus:78651376375
- pmid:20874741
- ISSN
- 1651-2227
- DOI
- 10.1111/j.1651-2227.2010.02027.x
- language
- English
- LU publication?
- yes
- id
- 8fdbc5e4-bbdd-4fd5-9d46-6c1cc5c35dff (old id 2295900)
- date added to LUP
- 2016-04-01 13:06:21
- date last changed
- 2023-09-02 18:57:55
@article{8fdbc5e4-bbdd-4fd5-9d46-6c1cc5c35dff,
abstract = {{Aim: To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment. Methods: Forty-five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24 +/- 6 and 72 +/- 6 h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA/Ao) ratio and Doppler pixels representing ductal shunting. Results: Twenty-eight infants had a PDA with a detectable left-to-right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a sensitivity of 89%, a specificity of 70%, a positive likelihood ratio of 2.97 and a negative likelihood ratio of 0.16 at the age of 72 h. The efficacy of the method at 72 h of age was 84%. The corresponding efficacy of the pulsatile Doppler curve was 72%, percentage of green colour pixels 63% and the LA/Ao ratio 53%. Conclusion: Ductus diameter appears to be the most important variable in determining the need for therapeutic intervention for PDA in preterm infants.}},
author = {{Harling, S. and Pupp, Ingrid and Baigi, A. and Pesonen, E.}},
issn = {{1651-2227}},
keywords = {{Colour Doppler echocardiography; Patent ductus arteriosus; Prediction; Very low birthweight infant}},
language = {{eng}},
number = {{2}},
pages = {{231--235}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Pædiatrica}},
title = {{Echocardiographic prediction of patent ductus arteriosus in need of therapeutic intervention}},
url = {{http://dx.doi.org/10.1111/j.1651-2227.2010.02027.x}},
doi = {{10.1111/j.1651-2227.2010.02027.x}},
volume = {{100}},
year = {{2011}},
}