Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness.

Nilsson, Karin LU ; Gustafson, Lars LU and Hultberg, Björn LU (2012) In Dementia and Geriatric Cognitive Disorders Extra 2. p.10-18
Abstract
BACKGROUND:

Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.



METHOD:

In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.



RESULTS AND CONCLUSION:

Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease... (More)
BACKGROUND:

Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.



METHOD:

In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.



RESULTS AND CONCLUSION:

Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease and normal NT-proBNP level. Thus, elevated serum NT-proBNP level might be helpful to detect patients who have a more severe cardiovascular disease. (Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Dementia and Geriatric Cognitive Disorders Extra
volume
2
pages
10 - 18
publisher
Karger
external identifiers
  • pmid:22479261
ISSN
1664-5464
DOI
10.1159/000334997
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Department of Psychogeriatrics (013304000)
id
f11d08e8-ad91-4917-ae93-8e3b89b2c1b0 (old id 2519765)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22479261?dopt=Abstract
date added to LUP
2016-04-04 09:11:40
date last changed
2018-11-21 20:51:25
@article{f11d08e8-ad91-4917-ae93-8e3b89b2c1b0,
  abstract     = {{BACKGROUND:<br/><br>
Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.<br/><br>
<br/><br>
METHOD:<br/><br>
In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.<br/><br>
<br/><br>
RESULTS AND CONCLUSION:<br/><br>
Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease and normal NT-proBNP level. Thus, elevated serum NT-proBNP level might be helpful to detect patients who have a more severe cardiovascular disease.}},
  author       = {{Nilsson, Karin and Gustafson, Lars and Hultberg, Björn}},
  issn         = {{1664-5464}},
  language     = {{eng}},
  pages        = {{10--18}},
  publisher    = {{Karger}},
  series       = {{Dementia and Geriatric Cognitive Disorders Extra}},
  title        = {{The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness.}},
  url          = {{http://dx.doi.org/10.1159/000334997}},
  doi          = {{10.1159/000334997}},
  volume       = {{2}},
  year         = {{2012}},
}