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Intracerebral Infections as a Complication of Deep Brain Stimulation

Blomstedt, Patric and Bjartmarz, Hjalmar LU (2012) In Stereotactic and Functional Neurosurgery 90(2). p.92-96
Abstract
Background: Intracerebral infections after deep brain stimulation (DBS) are rare. The published material is limited to 2 case reports. A review of 20 publications of 3,818 patients focusing on complications of DBS did not reveal one single case. For that reason, we decided to present our own experience of 4 patients with this complication. Objectives: To analyze and present our material regarding intracerebral infections after DBS. Methods: Four patients with intracerebral infection after DBS were retrospectively analyzed. Results: The 4 patients exhibited signs of intracerebral infection 2-14 days after DBS for Parkinson's disease. CT and MRI verified signs of possible cerebral involvement. In 3 patients, positive cultures were obtained... (More)
Background: Intracerebral infections after deep brain stimulation (DBS) are rare. The published material is limited to 2 case reports. A review of 20 publications of 3,818 patients focusing on complications of DBS did not reveal one single case. For that reason, we decided to present our own experience of 4 patients with this complication. Objectives: To analyze and present our material regarding intracerebral infections after DBS. Methods: Four patients with intracerebral infection after DBS were retrospectively analyzed. Results: The 4 patients exhibited signs of intracerebral infection 2-14 days after DBS for Parkinson's disease. CT and MRI verified signs of possible cerebral involvement. In 3 patients, positive cultures were obtained from the extracted electrodes. All patients recovered completely following treatment with antibiotics and removal of the implanted hardware. Two of the patients were later re-implanted. Conclusions: Intracerebral infection is a rare complication of DBS. It does, however, occur occasionally and should be taken into consideration when evaluating the risks of DBS. Copyright (c) 2012 S. Karger AG, Basel (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Abscess, Deep brain stimulation, Intracerebral infection
in
Stereotactic and Functional Neurosurgery
volume
90
issue
2
pages
92 - 96
publisher
Karger
external identifiers
  • wos:000303490800004
  • scopus:84857133860
ISSN
1011-6125
DOI
10.1159/000335712
language
English
LU publication?
yes
id
6ddae6bf-d810-449a-b38e-c232fd74a515 (old id 2562918)
date added to LUP
2016-04-01 13:34:49
date last changed
2022-05-19 20:03:12
@article{6ddae6bf-d810-449a-b38e-c232fd74a515,
  abstract     = {{Background: Intracerebral infections after deep brain stimulation (DBS) are rare. The published material is limited to 2 case reports. A review of 20 publications of 3,818 patients focusing on complications of DBS did not reveal one single case. For that reason, we decided to present our own experience of 4 patients with this complication. Objectives: To analyze and present our material regarding intracerebral infections after DBS. Methods: Four patients with intracerebral infection after DBS were retrospectively analyzed. Results: The 4 patients exhibited signs of intracerebral infection 2-14 days after DBS for Parkinson's disease. CT and MRI verified signs of possible cerebral involvement. In 3 patients, positive cultures were obtained from the extracted electrodes. All patients recovered completely following treatment with antibiotics and removal of the implanted hardware. Two of the patients were later re-implanted. Conclusions: Intracerebral infection is a rare complication of DBS. It does, however, occur occasionally and should be taken into consideration when evaluating the risks of DBS. Copyright (c) 2012 S. Karger AG, Basel}},
  author       = {{Blomstedt, Patric and Bjartmarz, Hjalmar}},
  issn         = {{1011-6125}},
  keywords     = {{Abscess; Deep brain stimulation; Intracerebral infection}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{92--96}},
  publisher    = {{Karger}},
  series       = {{Stereotactic and Functional Neurosurgery}},
  title        = {{Intracerebral Infections as a Complication of Deep Brain Stimulation}},
  url          = {{http://dx.doi.org/10.1159/000335712}},
  doi          = {{10.1159/000335712}},
  volume       = {{90}},
  year         = {{2012}},
}