7-T MR-from research to clinical applications?
(2012) In NMR in Biomedicine 25(5). p.695-716- Abstract
- Over 20?000 MR systems are currently installed worldwide and, although the majority operate at magnetic fields of 1.5?T and below (i.e. about 70%), experience with 3-T (in high-field clinical diagnostic imaging and research) and 7-T (research only) human MR scanners points to a future in functional and metabolic MR diagnostics. Complementary to previous studies, this review attempts to provide an overview of ultrahigh-field MR research with special emphasis on emerging clinical applications at 7?T. We provide a short summary of the technical development and the current status of installed MR systems. The advantages and challenges of ultrahigh-field MRI and MRS are discussed with special emphasis on radiofrequency inhomogeneity, relaxation... (More)
- Over 20?000 MR systems are currently installed worldwide and, although the majority operate at magnetic fields of 1.5?T and below (i.e. about 70%), experience with 3-T (in high-field clinical diagnostic imaging and research) and 7-T (research only) human MR scanners points to a future in functional and metabolic MR diagnostics. Complementary to previous studies, this review attempts to provide an overview of ultrahigh-field MR research with special emphasis on emerging clinical applications at 7?T. We provide a short summary of the technical development and the current status of installed MR systems. The advantages and challenges of ultrahigh-field MRI and MRS are discussed with special emphasis on radiofrequency inhomogeneity, relaxation times, signal-to-noise improvements, susceptibility effects, chemical shifts, specific absorption rate and other safety issues. In terms of applications, we focus on the topics most likely to gain significantly from 7-T MR, i.e. brain imaging and spectroscopy and musculoskeletal imaging, but also body imaging, which is particularly challenging. Examples are given to demonstrate the advantages of susceptibility-weighted imaging, time-of-flight MR angiography, high-resolution functional MRI, 1H and 31P MRSI in the human brain, sodium and functional imaging of cartilage and the first results (and artefacts) using an eight-channel body array, suggesting future areas of research that should be intensified in order to fully explore the potential of 7-T MR systems for use in clinical diagnosis. Copyright (C) 2011 John Wiley & Sons, Ltd. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2570952
- author
- Moser, Ewald ; Ståhlberg, Freddy LU ; Ladd, Mark E. and Trattnig, Siegfried
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- skeletal muscle, cartilage, brain, safety, ultrahigh-field MR, 7-T, vascular, heart
- in
- NMR in Biomedicine
- volume
- 25
- issue
- 5
- pages
- 695 - 716
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000302617600002
- scopus:84859646398
- pmid:22102481
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.1794
- language
- English
- LU publication?
- yes
- id
- cc71544e-c947-45ba-97f9-a966facecd55 (old id 2570952)
- date added to LUP
- 2016-04-01 10:51:47
- date last changed
- 2022-05-13 20:55:14
@article{cc71544e-c947-45ba-97f9-a966facecd55,
abstract = {{Over 20?000 MR systems are currently installed worldwide and, although the majority operate at magnetic fields of 1.5?T and below (i.e. about 70%), experience with 3-T (in high-field clinical diagnostic imaging and research) and 7-T (research only) human MR scanners points to a future in functional and metabolic MR diagnostics. Complementary to previous studies, this review attempts to provide an overview of ultrahigh-field MR research with special emphasis on emerging clinical applications at 7?T. We provide a short summary of the technical development and the current status of installed MR systems. The advantages and challenges of ultrahigh-field MRI and MRS are discussed with special emphasis on radiofrequency inhomogeneity, relaxation times, signal-to-noise improvements, susceptibility effects, chemical shifts, specific absorption rate and other safety issues. In terms of applications, we focus on the topics most likely to gain significantly from 7-T MR, i.e. brain imaging and spectroscopy and musculoskeletal imaging, but also body imaging, which is particularly challenging. Examples are given to demonstrate the advantages of susceptibility-weighted imaging, time-of-flight MR angiography, high-resolution functional MRI, 1H and 31P MRSI in the human brain, sodium and functional imaging of cartilage and the first results (and artefacts) using an eight-channel body array, suggesting future areas of research that should be intensified in order to fully explore the potential of 7-T MR systems for use in clinical diagnosis. Copyright (C) 2011 John Wiley & Sons, Ltd.}},
author = {{Moser, Ewald and Ståhlberg, Freddy and Ladd, Mark E. and Trattnig, Siegfried}},
issn = {{0952-3480}},
keywords = {{skeletal muscle; cartilage; brain; safety; ultrahigh-field MR; 7-T; vascular; heart}},
language = {{eng}},
number = {{5}},
pages = {{695--716}},
publisher = {{John Wiley & Sons Inc.}},
series = {{NMR in Biomedicine}},
title = {{7-T MR-from research to clinical applications?}},
url = {{http://dx.doi.org/10.1002/nbm.1794}},
doi = {{10.1002/nbm.1794}},
volume = {{25}},
year = {{2012}},
}