Effect of maternal age on uterine flow impedance
(2005) In Journal of Clinical Ultrasound 33(1). p.14-17- Abstract
- Purpose. This study was conducted to determine possible maternal age-related changes in uterine artery impedance in normal late pregnancy. Patients and Methods. In a cross-sectional design study, Doppler velocimetry of the uterine vessels was performed in 884 pregnant women with normal, late, singleton pregnancies. We hypothesized that maternal age is associated with changes in uterine blood flow Doppler parameters. We tested for univariate associations and for an adjusted relationship between these factors using a multivariate model to control for confounders. Results. We found a statistically significant, nonlinear relationship between mean uterine artery impedance (pulsatility index) and maternal age, with an increase of the pulsatility... (More)
- Purpose. This study was conducted to determine possible maternal age-related changes in uterine artery impedance in normal late pregnancy. Patients and Methods. In a cross-sectional design study, Doppler velocimetry of the uterine vessels was performed in 884 pregnant women with normal, late, singleton pregnancies. We hypothesized that maternal age is associated with changes in uterine blood flow Doppler parameters. We tested for univariate associations and for an adjusted relationship between these factors using a multivariate model to control for confounders. Results. We found a statistically significant, nonlinear relationship between mean uterine artery impedance (pulsatility index) and maternal age, with an increase of the pulsatility index in women above the age of 35. This association continued to be significant even when adjusted for gestational age and parity as confounders. Conclusions. In normal pregnancy, an increase in uterine artery impedance was noted in women above the age of 35. This finding may be related to the physiologic process of aging and may partly explain why pregnancies in older women are associated with diverse complications more often than those in younger women. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/257813
- author
- Pirhonen, J ; Bergersen, TK ; Abdlenoor, M ; Dubiel, M and Gudmundsson, Saemundur LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- normal pregnancy, uterus, maternal age, blood flow, Doppler ultrasonography, index, pulsatility
- in
- Journal of Clinical Ultrasound
- volume
- 33
- issue
- 1
- pages
- 14 - 17
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:15690442
- wos:000226005800004
- scopus:10944258367
- ISSN
- 0091-2751
- DOI
- 10.1002/jcu.20079
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- a50cbee6-06a4-4d2a-9f62-6e6541580ea9 (old id 257813)
- date added to LUP
- 2016-04-01 15:21:50
- date last changed
- 2022-01-28 04:59:40
@article{a50cbee6-06a4-4d2a-9f62-6e6541580ea9,
abstract = {{Purpose. This study was conducted to determine possible maternal age-related changes in uterine artery impedance in normal late pregnancy. Patients and Methods. In a cross-sectional design study, Doppler velocimetry of the uterine vessels was performed in 884 pregnant women with normal, late, singleton pregnancies. We hypothesized that maternal age is associated with changes in uterine blood flow Doppler parameters. We tested for univariate associations and for an adjusted relationship between these factors using a multivariate model to control for confounders. Results. We found a statistically significant, nonlinear relationship between mean uterine artery impedance (pulsatility index) and maternal age, with an increase of the pulsatility index in women above the age of 35. This association continued to be significant even when adjusted for gestational age and parity as confounders. Conclusions. In normal pregnancy, an increase in uterine artery impedance was noted in women above the age of 35. This finding may be related to the physiologic process of aging and may partly explain why pregnancies in older women are associated with diverse complications more often than those in younger women.}},
author = {{Pirhonen, J and Bergersen, TK and Abdlenoor, M and Dubiel, M and Gudmundsson, Saemundur}},
issn = {{0091-2751}},
keywords = {{normal pregnancy; uterus; maternal age; blood flow; Doppler ultrasonography; index; pulsatility}},
language = {{eng}},
number = {{1}},
pages = {{14--17}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Journal of Clinical Ultrasound}},
title = {{Effect of maternal age on uterine flow impedance}},
url = {{http://dx.doi.org/10.1002/jcu.20079}},
doi = {{10.1002/jcu.20079}},
volume = {{33}},
year = {{2005}},
}