Evolution of photosensory pineal organs in new light: the fate of neurodocrine photoreceptors
(2003) In Philosophical Transactions of the Royal Society B: Biological Sciences 358(1438). p.1679-1700- Abstract
- Pineal evolution is envisaged as a gradual transformation of pinealocytes (a gradual regression of pinealocyte sensory capacity within a particular cell line), the so-called sensory cell line of the pineal organ. In most non-mammals the pineal organ is a directly photosensory organ, while the pineal organ of mammals (epiphysis cerebri) is a non-sensory neuroendocrine organ under photoperiod control. The phylogenetic transformation of the pineal organ is reflected in the morphology and physiology of the main parenchymal cell type, the pinealocyte. In anamniotes, pinealocytes with retinal cone photoreceptor-like characteristics predominate, whereas in sauropsids so-called rudimentary photoreceptors predominate. These have well-developed... (More)
- Pineal evolution is envisaged as a gradual transformation of pinealocytes (a gradual regression of pinealocyte sensory capacity within a particular cell line), the so-called sensory cell line of the pineal organ. In most non-mammals the pineal organ is a directly photosensory organ, while the pineal organ of mammals (epiphysis cerebri) is a non-sensory neuroendocrine organ under photoperiod control. The phylogenetic transformation of the pineal organ is reflected in the morphology and physiology of the main parenchymal cell type, the pinealocyte. In anamniotes, pinealocytes with retinal cone photoreceptor-like characteristics predominate, whereas in sauropsids so-called rudimentary photoreceptors predominate. These have well-developed secretory characteristics, and have been interpreted as intermediaries between the anamniote pineal photoreceptors and the mammalian non-sensory pinealocytes. We have re-examined the original studies on which the gradual transformation hypothesis of pineal evolution is based, and found that the evidence for this model of pineal evolution is ambiguous. In the light of recent advances in the understanding of neural development mechanisms, we propose a new hypothesis of pineal evolution, in which the old notion 'gradual regression within the sensory cell line' should be replaced with 'changes in fate restriction within the neural lineage of the pineal field'. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/297007
- author
- Ekström, Peter LU and Meissl, Hilmar
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- vertebrate photoreceptors, electron, microscopy, melatonin, opsin, pineal gland
- in
- Philosophical Transactions of the Royal Society B: Biological Sciences
- volume
- 358
- issue
- 1438
- pages
- 1679 - 1700
- publisher
- Royal Society Publishing
- external identifiers
-
- pmid:14561326
- wos:000186255500005
- scopus:0142216226
- ISSN
- 1471-2970
- DOI
- 10.1098/rstb.2003.1303
- language
- English
- LU publication?
- yes
- id
- fcb0dbc3-f954-4301-be34-317c4a57267a (old id 297007)
- date added to LUP
- 2016-04-01 16:33:37
- date last changed
- 2022-01-28 20:34:01
@article{fcb0dbc3-f954-4301-be34-317c4a57267a,
abstract = {{Pineal evolution is envisaged as a gradual transformation of pinealocytes (a gradual regression of pinealocyte sensory capacity within a particular cell line), the so-called sensory cell line of the pineal organ. In most non-mammals the pineal organ is a directly photosensory organ, while the pineal organ of mammals (epiphysis cerebri) is a non-sensory neuroendocrine organ under photoperiod control. The phylogenetic transformation of the pineal organ is reflected in the morphology and physiology of the main parenchymal cell type, the pinealocyte. In anamniotes, pinealocytes with retinal cone photoreceptor-like characteristics predominate, whereas in sauropsids so-called rudimentary photoreceptors predominate. These have well-developed secretory characteristics, and have been interpreted as intermediaries between the anamniote pineal photoreceptors and the mammalian non-sensory pinealocytes. We have re-examined the original studies on which the gradual transformation hypothesis of pineal evolution is based, and found that the evidence for this model of pineal evolution is ambiguous. In the light of recent advances in the understanding of neural development mechanisms, we propose a new hypothesis of pineal evolution, in which the old notion 'gradual regression within the sensory cell line' should be replaced with 'changes in fate restriction within the neural lineage of the pineal field'.}},
author = {{Ekström, Peter and Meissl, Hilmar}},
issn = {{1471-2970}},
keywords = {{vertebrate photoreceptors; electron; microscopy; melatonin; opsin; pineal gland}},
language = {{eng}},
number = {{1438}},
pages = {{1679--1700}},
publisher = {{Royal Society Publishing}},
series = {{Philosophical Transactions of the Royal Society B: Biological Sciences}},
title = {{Evolution of photosensory pineal organs in new light: the fate of neurodocrine photoreceptors}},
url = {{http://dx.doi.org/10.1098/rstb.2003.1303}},
doi = {{10.1098/rstb.2003.1303}},
volume = {{358}},
year = {{2003}},
}