Cost effectiveness of nasal budesonide versus surgical treatment for nasal polyps
(2003) In PharmacoEconomics 21(5). p.351-356- Abstract
- Objective: To conduct a cost-effectiveness study of nasal budesonide versus surgical treatment in the management of nasal polyps. Design and methods: A decision-tree model reflecting two different treatment strategies for nasal polyps in Sweden was developed. The first strategy was initial polypectomy, performed under three different sets of circumstances: inpatient functional endoscopic surgery, outpatient evulsion with sedation, or outpatient evulsion with local anaesthesia; all treatments were followed by intranasal treatment with budesonide (Rhinocort(R)) 128mug twice daily. The second strategy was initial intranasal treatment with budesonide 128mug twice daily. Perspective: Healthcare provider perspective. Outcome measures and... (More)
- Objective: To conduct a cost-effectiveness study of nasal budesonide versus surgical treatment in the management of nasal polyps. Design and methods: A decision-tree model reflecting two different treatment strategies for nasal polyps in Sweden was developed. The first strategy was initial polypectomy, performed under three different sets of circumstances: inpatient functional endoscopic surgery, outpatient evulsion with sedation, or outpatient evulsion with local anaesthesia; all treatments were followed by intranasal treatment with budesonide (Rhinocort(R)) 128mug twice daily. The second strategy was initial intranasal treatment with budesonide 128mug twice daily. Perspective: Healthcare provider perspective. Outcome measures and results: After 1 month, treatment with nasal budesonide was classified as a success (82.5%) or a failure (17.5%) based on clinical study data. In cases of success, the treatment was continued, and in cases of failure, polypectomy was undertaken, followed by budesonide 128mug twice daily. Treatments were evaluated after 4 months using prices from the Central Hospital in Skovde, Sweden. The expected reduction in cost from using initial nasal budesonide treatment compared with the different alternatives of polypectomy were 9760 Swedish kronors (SEK) for inpatient functional endoscopic surgery, SEK2747 for outpatient evulsion with sedation, and SEK672 for outpatient evulsion with anaesthesia (1998 values). Nasal budesonide 128 mug twice daily treatment for nasal polyps revealed a potential reduction in costs of 53% compared with the primary surgery approach. Conclusion: Initial treatment of nasal polyps with nasal budesonide provides lower costs than treatment with initial polypectomy with maintained effectiveness. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/313274
- author
- Berggren, Fredrik LU and Johansson, L
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PharmacoEconomics
- volume
- 21
- issue
- 5
- pages
- 351 - 356
- publisher
- Adis International
- external identifiers
-
- wos:000182092500006
- pmid:12627988
- scopus:0037248027
- ISSN
- 1179-2027
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Lund University Centre for Health Economics (LUCHE) (016630120), Division of Health Economics and Forensic Medicine (Closed 2012) (013040050)
- id
- 4d6d7711-51e7-4592-9e2d-f28a723d21d7 (old id 313274)
- alternative location
- http://www.ingentaconnect.com/content/adis/pec/2003/00000021/00000005/art00006
- date added to LUP
- 2016-04-01 16:31:56
- date last changed
- 2022-02-27 21:51:06
@article{4d6d7711-51e7-4592-9e2d-f28a723d21d7,
abstract = {{Objective: To conduct a cost-effectiveness study of nasal budesonide versus surgical treatment in the management of nasal polyps. Design and methods: A decision-tree model reflecting two different treatment strategies for nasal polyps in Sweden was developed. The first strategy was initial polypectomy, performed under three different sets of circumstances: inpatient functional endoscopic surgery, outpatient evulsion with sedation, or outpatient evulsion with local anaesthesia; all treatments were followed by intranasal treatment with budesonide (Rhinocort(R)) 128mug twice daily. The second strategy was initial intranasal treatment with budesonide 128mug twice daily. Perspective: Healthcare provider perspective. Outcome measures and results: After 1 month, treatment with nasal budesonide was classified as a success (82.5%) or a failure (17.5%) based on clinical study data. In cases of success, the treatment was continued, and in cases of failure, polypectomy was undertaken, followed by budesonide 128mug twice daily. Treatments were evaluated after 4 months using prices from the Central Hospital in Skovde, Sweden. The expected reduction in cost from using initial nasal budesonide treatment compared with the different alternatives of polypectomy were 9760 Swedish kronors (SEK) for inpatient functional endoscopic surgery, SEK2747 for outpatient evulsion with sedation, and SEK672 for outpatient evulsion with anaesthesia (1998 values). Nasal budesonide 128 mug twice daily treatment for nasal polyps revealed a potential reduction in costs of 53% compared with the primary surgery approach. Conclusion: Initial treatment of nasal polyps with nasal budesonide provides lower costs than treatment with initial polypectomy with maintained effectiveness.}},
author = {{Berggren, Fredrik and Johansson, L}},
issn = {{1179-2027}},
language = {{eng}},
number = {{5}},
pages = {{351--356}},
publisher = {{Adis International}},
series = {{PharmacoEconomics}},
title = {{Cost effectiveness of nasal budesonide versus surgical treatment for nasal polyps}},
url = {{http://www.ingentaconnect.com/content/adis/pec/2003/00000021/00000005/art00006}},
volume = {{21}},
year = {{2003}},
}