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Orientational correlations in confined DNA

Werner, E. ; Persson, F. ; Westerlund, F. ; Tegenfeldt, Jonas LU orcid and Mehlig, B. (2012) In Physical Review E (Statistical, Nonlinear, and Soft Matter Physics) 86(4). p.041802-041802
Abstract
We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)
volume
86
issue
4
pages
041802 - 041802
publisher
American Physical Society
external identifiers
  • wos:000309731700005
  • scopus:84867533563
  • pmid:23214605
ISSN
1539-3755
DOI
10.1103/PhysRevE.86.041802
language
English
LU publication?
yes
additional info
4
id
397ff7d1-776f-4454-a896-b01fff0d0540 (old id 3224875)
date added to LUP
2016-04-01 10:01:42
date last changed
2022-04-04 01:38:53
@article{397ff7d1-776f-4454-a896-b01fff0d0540,
  abstract     = {{We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.}},
  author       = {{Werner, E. and Persson, F. and Westerlund, F. and Tegenfeldt, Jonas and Mehlig, B.}},
  issn         = {{1539-3755}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{041802--041802}},
  publisher    = {{American Physical Society}},
  series       = {{Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)}},
  title        = {{Orientational correlations in confined DNA}},
  url          = {{http://dx.doi.org/10.1103/PhysRevE.86.041802}},
  doi          = {{10.1103/PhysRevE.86.041802}},
  volume       = {{86}},
  year         = {{2012}},
}