Orientational correlations in confined DNA
(2012) In Physical Review E (Statistical, Nonlinear, and Soft Matter Physics) 86(4). p.041802-041802- Abstract
- We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3224875
- author
- Werner, E. ; Persson, F. ; Westerlund, F. ; Tegenfeldt, Jonas LU and Mehlig, B.
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)
- volume
- 86
- issue
- 4
- pages
- 041802 - 041802
- publisher
- American Physical Society
- external identifiers
-
- wos:000309731700005
- scopus:84867533563
- pmid:23214605
- ISSN
- 1539-3755
- DOI
- 10.1103/PhysRevE.86.041802
- language
- English
- LU publication?
- yes
- additional info
- 4
- id
- 397ff7d1-776f-4454-a896-b01fff0d0540 (old id 3224875)
- date added to LUP
- 2016-04-01 10:01:42
- date last changed
- 2022-04-04 01:38:53
@article{397ff7d1-776f-4454-a896-b01fff0d0540, abstract = {{We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.}}, author = {{Werner, E. and Persson, F. and Westerlund, F. and Tegenfeldt, Jonas and Mehlig, B.}}, issn = {{1539-3755}}, language = {{eng}}, number = {{4}}, pages = {{041802--041802}}, publisher = {{American Physical Society}}, series = {{Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)}}, title = {{Orientational correlations in confined DNA}}, url = {{http://dx.doi.org/10.1103/PhysRevE.86.041802}}, doi = {{10.1103/PhysRevE.86.041802}}, volume = {{86}}, year = {{2012}}, }