Changes in forearm bone mass and bone size after menopause - A mean 24-year prospective study.
(2012) In Journal of Musculoskeletal and Neuronal Interactions - Jmni 12(4). p.192-198- Abstract
- Objective: Bone loss and periosteal expansion is found after menopause. The accelerated early postmenopausal bone loss is not permanent but if the same accounts for the periosteal expansion is unknown. Methods: Bone mineral density (BMD) and skeletal structure of the distal forearm were followed from menopause and on average 24 years (range 18-28) by single-photon absorptiometry at 12 occasions in a population-based sample of 81 Caucasian women with no medication or disease affecting bone metabolism. A Strength Index based on areal BMD and bone structure was calculated. Postmenopausal serum-estradiol levels and incident distal radius fractures were registered. Data are presented as means with 95% confidence interval (95% CI). Results: The... (More)
- Objective: Bone loss and periosteal expansion is found after menopause. The accelerated early postmenopausal bone loss is not permanent but if the same accounts for the periosteal expansion is unknown. Methods: Bone mineral density (BMD) and skeletal structure of the distal forearm were followed from menopause and on average 24 years (range 18-28) by single-photon absorptiometry at 12 occasions in a population-based sample of 81 Caucasian women with no medication or disease affecting bone metabolism. A Strength Index based on areal BMD and bone structure was calculated. Postmenopausal serum-estradiol levels and incident distal radius fractures were registered. Data are presented as means with 95% confidence interval (95% CI). Results: The annual BMD loss in three periods, 0-8, 8-16 and 16-28 years after menopause, was 2.0% (1.6, 2.4), 1.0% (0.6, 1.4) and 1.0% (0.7, 1.3), respectively. The annual periosteal expansion was 1.0% (0.8, 1.3), 0.0% (-0.3, 0.3) and 0.0% (-0.2, 0.2), respectively. Mean post-menopausal oestrogen levels correlated moderately with annual loss in aBMD (r=0.51, p<0.001) but less with the annual changes in bone width (r= -0.22, p=0.06). Conclusion: Postmenopausal periosteal expansion in the distal forearm seems to occur only in the first postmenopausal decade. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3347833
- author
- Svejme, Ola LU ; Ahlborg, Henrik LU and Karlsson, Magnus LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Musculoskeletal and Neuronal Interactions - Jmni
- volume
- 12
- issue
- 4
- pages
- 192 - 198
- publisher
- International Society of Musculoskeletal and Neuronal Interactions
- external identifiers
-
- wos:000313419100001
- pmid:23196261
- scopus:84870825899
- ISSN
- 1108-7161
- language
- English
- LU publication?
- yes
- id
- a2dd1cca-07f7-4e44-893b-828760e83941 (old id 3347833)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23196261?dopt=Abstract
- date added to LUP
- 2016-04-04 09:25:38
- date last changed
- 2022-01-29 17:49:18
@article{a2dd1cca-07f7-4e44-893b-828760e83941,
abstract = {{Objective: Bone loss and periosteal expansion is found after menopause. The accelerated early postmenopausal bone loss is not permanent but if the same accounts for the periosteal expansion is unknown. Methods: Bone mineral density (BMD) and skeletal structure of the distal forearm were followed from menopause and on average 24 years (range 18-28) by single-photon absorptiometry at 12 occasions in a population-based sample of 81 Caucasian women with no medication or disease affecting bone metabolism. A Strength Index based on areal BMD and bone structure was calculated. Postmenopausal serum-estradiol levels and incident distal radius fractures were registered. Data are presented as means with 95% confidence interval (95% CI). Results: The annual BMD loss in three periods, 0-8, 8-16 and 16-28 years after menopause, was 2.0% (1.6, 2.4), 1.0% (0.6, 1.4) and 1.0% (0.7, 1.3), respectively. The annual periosteal expansion was 1.0% (0.8, 1.3), 0.0% (-0.3, 0.3) and 0.0% (-0.2, 0.2), respectively. Mean post-menopausal oestrogen levels correlated moderately with annual loss in aBMD (r=0.51, p<0.001) but less with the annual changes in bone width (r= -0.22, p=0.06). Conclusion: Postmenopausal periosteal expansion in the distal forearm seems to occur only in the first postmenopausal decade.}},
author = {{Svejme, Ola and Ahlborg, Henrik and Karlsson, Magnus}},
issn = {{1108-7161}},
language = {{eng}},
number = {{4}},
pages = {{192--198}},
publisher = {{International Society of Musculoskeletal and Neuronal Interactions}},
series = {{Journal of Musculoskeletal and Neuronal Interactions - Jmni}},
title = {{Changes in forearm bone mass and bone size after menopause - A mean 24-year prospective study.}},
url = {{http://www.ncbi.nlm.nih.gov/pubmed/23196261?dopt=Abstract}},
volume = {{12}},
year = {{2012}},
}