A novel blood-based biomarker for detection of autism spectrum disorders.
(2012) In Translational Psychiatry 2(3). p.91-91- Abstract
- Autism spectrum disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to the development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/peptides that may be used as biomarkers for detection of the disorders. Three differentially expressed peptides with mass-charge (m/z) values of 2020 ± 1, 1864 ± 1 and 1978 ± 1 Da in the heparin plasma of children with ASD that were significantly changed as compared with the peptide pattern of the non-ASD control group are reported here. This novel... (More)
- Autism spectrum disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to the development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/peptides that may be used as biomarkers for detection of the disorders. Three differentially expressed peptides with mass-charge (m/z) values of 2020 ± 1, 1864 ± 1 and 1978 ± 1 Da in the heparin plasma of children with ASD that were significantly changed as compared with the peptide pattern of the non-ASD control group are reported here. This novel set of biomarkers allows for a reliable blood-based diagnostic tool that may be used in diagnosis and potentially, in prognosis of ASD (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3459575
- author
- N, Momeni ; J, Bergquist ; F, Behnia ; Sivberg, Bengt LU ; M. T., Joghataei and B. L., Persson
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Translational Psychiatry
- volume
- 2
- issue
- 3
- pages
- 91 - 91
- publisher
- Nature Publishing Group
- external identifiers
-
- wos:000315990800007
- scopus:84858021906
- pmid:22832856
- ISSN
- 2158-3188
- DOI
- 10.1038/tp.2012.19
- language
- English
- LU publication?
- yes
- id
- 9b968858-61c5-45b6-9770-7dea022a2f77 (old id 3459575)
- alternative location
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309533/
- date added to LUP
- 2016-04-01 13:11:26
- date last changed
- 2022-04-21 20:18:36
@article{9b968858-61c5-45b6-9770-7dea022a2f77,
abstract = {{Autism spectrum disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to the development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/peptides that may be used as biomarkers for detection of the disorders. Three differentially expressed peptides with mass-charge (m/z) values of 2020 ± 1, 1864 ± 1 and 1978 ± 1 Da in the heparin plasma of children with ASD that were significantly changed as compared with the peptide pattern of the non-ASD control group are reported here. This novel set of biomarkers allows for a reliable blood-based diagnostic tool that may be used in diagnosis and potentially, in prognosis of ASD}},
author = {{N, Momeni and J, Bergquist and F, Behnia and Sivberg, Bengt and M. T., Joghataei and B. L., Persson}},
issn = {{2158-3188}},
language = {{eng}},
number = {{3}},
pages = {{91--91}},
publisher = {{Nature Publishing Group}},
series = {{Translational Psychiatry}},
title = {{A novel blood-based biomarker for detection of autism spectrum disorders.}},
url = {{https://lup.lub.lu.se/search/files/3214245/3910339.pdf}},
doi = {{10.1038/tp.2012.19}},
volume = {{2}},
year = {{2012}},
}