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Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays

Mattiasson, B. LU ; Teeparuksapun, K. LU ; Lebogang, L. LU and Hedström, M. LU (2017) In Trends in Biotechnology 35(11). p.1021-1024
Abstract

It is possible to improve the sensitivity of immunoassays by several orders of magnitude by exploiting nanoenvironmental effects. This approach can detect trace amounts of compounds and will better illuminate the presence of signal substances in biological systems. Here we describe a method for ultrasensitive immunoassays using 'normal' antibodies (Abs).

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Capacitive biosensor, Immunoassay, Nanoenvironment, Ultrasensitive
in
Trends in Biotechnology
volume
35
issue
11
pages
1021 - 1024
publisher
Elsevier
external identifiers
  • scopus:85029686601
  • pmid:28943030
  • wos:000413234900003
ISSN
0167-7799
DOI
10.1016/j.tibtech.2017.06.001
language
English
LU publication?
yes
id
3bc11a75-8215-44b6-9e24-0fb7af02684f
date added to LUP
2017-10-09 13:15:29
date last changed
2024-01-14 06:54:02
@article{3bc11a75-8215-44b6-9e24-0fb7af02684f,
  abstract     = {{<p>It is possible to improve the sensitivity of immunoassays by several orders of magnitude by exploiting nanoenvironmental effects. This approach can detect trace amounts of compounds and will better illuminate the presence of signal substances in biological systems. Here we describe a method for ultrasensitive immunoassays using 'normal' antibodies (Abs).</p>}},
  author       = {{Mattiasson, B. and Teeparuksapun, K. and Lebogang, L. and Hedström, M.}},
  issn         = {{0167-7799}},
  keywords     = {{Capacitive biosensor; Immunoassay; Nanoenvironment; Ultrasensitive}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{1021--1024}},
  publisher    = {{Elsevier}},
  series       = {{Trends in Biotechnology}},
  title        = {{Nanoenvironmental Effects Dramatically Influence the Sensitivity of Immunoassays}},
  url          = {{http://dx.doi.org/10.1016/j.tibtech.2017.06.001}},
  doi          = {{10.1016/j.tibtech.2017.06.001}},
  volume       = {{35}},
  year         = {{2017}},
}