miRNA in mycosis fungoides and skin inflammation.
(2013) In APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 121(11). p.1017-1019- Abstract
- In this mini-review, progress in our understanding of the link between miRNAs and cytokines in inflammatory skin diseases is highlighted with focus on miR-155 in mycosis fungoides (MF). MF is the most common variant of cutaneous T-cell lymphoma (CTCL) and is characterized by malignant T-cell proliferation in a chronic inflammatory environment in affected skin. Recent data show that miR-155 is expressed in situ by both malignant and non-malignant T cells, induced via the STAT5 signal pathway and IL-2Rbeta/gamma cytokines, and thus suggest the importance of miR-155 in malignant proliferation, clinical diagnosis, and prognosis in CTCL.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4143504
- author
- Persson, Jenny L LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
- volume
- 121
- issue
- 11
- pages
- 1017 - 1019
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000326027200001
- pmid:24106870
- scopus:84886309176
- pmid:24106870
- ISSN
- 1600-0463
- DOI
- 10.1111/apm.12186
- language
- English
- LU publication?
- yes
- id
- 1686d04e-1869-44cc-8783-5444019cf39b (old id 4143504)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24106870?dopt=Abstract
- date added to LUP
- 2016-04-01 10:56:02
- date last changed
- 2022-04-04 22:41:51
@article{1686d04e-1869-44cc-8783-5444019cf39b, abstract = {{In this mini-review, progress in our understanding of the link between miRNAs and cytokines in inflammatory skin diseases is highlighted with focus on miR-155 in mycosis fungoides (MF). MF is the most common variant of cutaneous T-cell lymphoma (CTCL) and is characterized by malignant T-cell proliferation in a chronic inflammatory environment in affected skin. Recent data show that miR-155 is expressed in situ by both malignant and non-malignant T cells, induced via the STAT5 signal pathway and IL-2Rbeta/gamma cytokines, and thus suggest the importance of miR-155 in malignant proliferation, clinical diagnosis, and prognosis in CTCL.}}, author = {{Persson, Jenny L}}, issn = {{1600-0463}}, language = {{eng}}, number = {{11}}, pages = {{1017--1019}}, publisher = {{John Wiley & Sons Inc.}}, series = {{APMIS : acta pathologica, microbiologica, et immunologica Scandinavica}}, title = {{miRNA in mycosis fungoides and skin inflammation.}}, url = {{http://dx.doi.org/10.1111/apm.12186}}, doi = {{10.1111/apm.12186}}, volume = {{121}}, year = {{2013}}, }