Familial colorectal cancer type X: genetic profiles and phenotypic features.
(2015) In Modern Pathology 28(1). p.30-36- Abstract
- Heredity is a major cause of colorectal cancer, but although several rare high-risk syndromes have been linked to disease-predisposing mutations, the genetic mechanisms are undetermined in the majority of families suspected of hereditary cancer. We review the clinical presentation, histopathologic features, and the genetic and epigenetic profiles of the familial colorectal cancer type X (FCCTX) syndrome with the aim to delineate tumor characteristics that may contribute to refined diagnostics and optimized tumor prevention.Modern Pathology advance online publication, 18 April 2014; doi:10.1038/modpathol.2014.49.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4429899
- author
- Dominguez, Mev LU ; Therkildsen, Christina LU ; Da Silva, Sabrina and Nilbert, Mef LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Modern Pathology
- volume
- 28
- issue
- 1
- pages
- 30 - 36
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:24743215
- wos:000347384200004
- scopus:84920703226
- pmid:24743215
- ISSN
- 1530-0285
- DOI
- 10.1038/modpathol.2014.49
- project
- Precision Medicine in Hereditary Cancer and Sarcoma; targeted surveillance, immunotherapy and individualized follow-up
- Precision Medicine in Hereditary Cancer and Sarcoma; targeted surveillance, immunotherapy and individualized follow-up
- language
- English
- LU publication?
- yes
- id
- 7e31bf4f-7ba1-4b45-b242-d3720f53de13 (old id 4429899)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24743215?dopt=Abstract
- date added to LUP
- 2016-04-01 09:48:14
- date last changed
- 2022-05-05 07:39:56
@article{7e31bf4f-7ba1-4b45-b242-d3720f53de13, abstract = {{Heredity is a major cause of colorectal cancer, but although several rare high-risk syndromes have been linked to disease-predisposing mutations, the genetic mechanisms are undetermined in the majority of families suspected of hereditary cancer. We review the clinical presentation, histopathologic features, and the genetic and epigenetic profiles of the familial colorectal cancer type X (FCCTX) syndrome with the aim to delineate tumor characteristics that may contribute to refined diagnostics and optimized tumor prevention.Modern Pathology advance online publication, 18 April 2014; doi:10.1038/modpathol.2014.49.}}, author = {{Dominguez, Mev and Therkildsen, Christina and Da Silva, Sabrina and Nilbert, Mef}}, issn = {{1530-0285}}, language = {{eng}}, number = {{1}}, pages = {{30--36}}, publisher = {{Nature Publishing Group}}, series = {{Modern Pathology}}, title = {{Familial colorectal cancer type X: genetic profiles and phenotypic features.}}, url = {{http://dx.doi.org/10.1038/modpathol.2014.49}}, doi = {{10.1038/modpathol.2014.49}}, volume = {{28}}, year = {{2015}}, }