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A critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part II: the meta-analyses.

Olofsson, Per LU ; Ayres-de-Campos, Diogo ; Kessler, Jörg ; Tendal, Britta ; Yli, Branka M and Devoe, Lawrence (2014) In Acta Obstetricia et Gynecologica Scandinavica 93(6). p.571-586
Abstract
We appraised the methodology, execution and quality of the five published meta-analyses that are based on the five randomized controlled trials (RCTs) which compared cardiotocography (CTG) +ST analysis to CTG. The meta-analyses contained errors, either created de novo in handling of original data, or from a failure to recognize essential differences among the RCTs, particularly in their inclusion criteria and outcome parameters. No meta-analysis contained complete and relevant data from all five RCTs. We believe that one RCT excluded in two of the meta-analyses should have been included, while one RCT that was included in all meta-analyses, should have been excluded. After correction of the uncovered errors and exclusion of the RCT that we... (More)
We appraised the methodology, execution and quality of the five published meta-analyses that are based on the five randomized controlled trials (RCTs) which compared cardiotocography (CTG) +ST analysis to CTG. The meta-analyses contained errors, either created de novo in handling of original data, or from a failure to recognize essential differences among the RCTs, particularly in their inclusion criteria and outcome parameters. No meta-analysis contained complete and relevant data from all five RCTs. We believe that one RCT excluded in two of the meta-analyses should have been included, while one RCT that was included in all meta-analyses, should have been excluded. After correction of the uncovered errors and exclusion of the RCT that we deemed inappropriate, our new meta-analysis showed that CTG+ST monitoring significantly reduces the fetal scalp blood sampling usage (risk ratio 0.64; 95% confidence interval 0.47-0.88), total operative delivery rate (0.93; 0.88-0.99), and metabolic acidosis rate (0.61; 0.41-0.91). This article is protected by copyright. All rights reserved. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Obstetricia et Gynecologica Scandinavica
volume
93
issue
6
pages
571 - 586
publisher
Wiley-Blackwell
external identifiers
  • pmid:24797318
  • wos:000337566200010
  • scopus:84901641480
ISSN
1600-0412
DOI
10.1111/aogs.12412
language
English
LU publication?
yes
id
545f2dfb-acdb-4adc-aace-9805bfae02a1 (old id 4455849)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24797318?dopt=Abstract
date added to LUP
2016-04-01 10:19:23
date last changed
2022-01-25 22:07:24
@article{545f2dfb-acdb-4adc-aace-9805bfae02a1,
  abstract     = {{We appraised the methodology, execution and quality of the five published meta-analyses that are based on the five randomized controlled trials (RCTs) which compared cardiotocography (CTG) +ST analysis to CTG. The meta-analyses contained errors, either created de novo in handling of original data, or from a failure to recognize essential differences among the RCTs, particularly in their inclusion criteria and outcome parameters. No meta-analysis contained complete and relevant data from all five RCTs. We believe that one RCT excluded in two of the meta-analyses should have been included, while one RCT that was included in all meta-analyses, should have been excluded. After correction of the uncovered errors and exclusion of the RCT that we deemed inappropriate, our new meta-analysis showed that CTG+ST monitoring significantly reduces the fetal scalp blood sampling usage (risk ratio 0.64; 95% confidence interval 0.47-0.88), total operative delivery rate (0.93; 0.88-0.99), and metabolic acidosis rate (0.61; 0.41-0.91). This article is protected by copyright. All rights reserved.}},
  author       = {{Olofsson, Per and Ayres-de-Campos, Diogo and Kessler, Jörg and Tendal, Britta and Yli, Branka M and Devoe, Lawrence}},
  issn         = {{1600-0412}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{571--586}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Obstetricia et Gynecologica Scandinavica}},
  title        = {{A critical appraisal of the evidence for using cardiotocography plus ECG ST interval analysis for fetal surveillance in labor. Part II: the meta-analyses.}},
  url          = {{http://dx.doi.org/10.1111/aogs.12412}},
  doi          = {{10.1111/aogs.12412}},
  volume       = {{93}},
  year         = {{2014}},
}