Risk of neurodisability and other long-term outcomes for infants born following assisted reproductive technologies.
(2014) In Seminars in Fetal & Neonatal Medicine 19(4). p.239-244- Abstract
- Children born after assisted reproductive technologies (ART) have an increased morbidity. The risk of developing cerebral palsy is nearly doubled and the risk of developing epilepsy is also higher. Behavioural problems including attention deficit/hyperactivity disorder may be more common in children born following ART than among naturally conceived children but the finding is uncertain. Data on autism are difficult to interpret. There may exist a small increase in the incidence of childhood cancer and there is greater evidence of an elevated risk of asthma. To some extent, these risks are mediated by neonatal complications including prematurity and low birth weight but some effects such as cerebral palsy are likely to be linked to the... (More)
- Children born after assisted reproductive technologies (ART) have an increased morbidity. The risk of developing cerebral palsy is nearly doubled and the risk of developing epilepsy is also higher. Behavioural problems including attention deficit/hyperactivity disorder may be more common in children born following ART than among naturally conceived children but the finding is uncertain. Data on autism are difficult to interpret. There may exist a small increase in the incidence of childhood cancer and there is greater evidence of an elevated risk of asthma. To some extent, these risks are mediated by neonatal complications including prematurity and low birth weight but some effects such as cerebral palsy are likely to be linked to the increased rate of multiple births after ART. Many of the neonatal complications after ART are most likely linked to parental subfertility and are less an effect of the ART technology. The possibility exists that imprinting errors, associated with subfertility and/or ART, may result in long-term morbidity. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4455920
- author
- Källén, Bengt LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Seminars in Fetal & Neonatal Medicine
- volume
- 19
- issue
- 4
- pages
- 239 - 244
- publisher
- Elsevier
- external identifiers
-
- pmid:24793634
- wos:000340699700005
- scopus:84904820750
- pmid:24793634
- ISSN
- 1878-0946
- DOI
- 10.1016/j.siny.2014.04.002
- language
- English
- LU publication?
- yes
- id
- e7aa90b4-18c8-4d89-8628-4c7d3fad7671 (old id 4455920)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24793634?dopt=Abstract
- date added to LUP
- 2016-04-01 10:14:43
- date last changed
- 2022-02-17 08:10:39
@article{e7aa90b4-18c8-4d89-8628-4c7d3fad7671,
abstract = {{Children born after assisted reproductive technologies (ART) have an increased morbidity. The risk of developing cerebral palsy is nearly doubled and the risk of developing epilepsy is also higher. Behavioural problems including attention deficit/hyperactivity disorder may be more common in children born following ART than among naturally conceived children but the finding is uncertain. Data on autism are difficult to interpret. There may exist a small increase in the incidence of childhood cancer and there is greater evidence of an elevated risk of asthma. To some extent, these risks are mediated by neonatal complications including prematurity and low birth weight but some effects such as cerebral palsy are likely to be linked to the increased rate of multiple births after ART. Many of the neonatal complications after ART are most likely linked to parental subfertility and are less an effect of the ART technology. The possibility exists that imprinting errors, associated with subfertility and/or ART, may result in long-term morbidity.}},
author = {{Källén, Bengt}},
issn = {{1878-0946}},
language = {{eng}},
number = {{4}},
pages = {{239--244}},
publisher = {{Elsevier}},
series = {{Seminars in Fetal & Neonatal Medicine}},
title = {{Risk of neurodisability and other long-term outcomes for infants born following assisted reproductive technologies.}},
url = {{http://dx.doi.org/10.1016/j.siny.2014.04.002}},
doi = {{10.1016/j.siny.2014.04.002}},
volume = {{19}},
year = {{2014}},
}