TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.
(2015) In Journal of Hypertension 33(6). p.1301-1309- Abstract
- Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment. Pharmacogenomics could be a useful tool to pinpoint gene variants involved in antihypertensive drug response, thus optimizing therapeutic advantages and minimizing side effects.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5143308
- author
- Chittani, Martina
; Zaninello, Roberta
; Lanzani, Chiara
; Frau, Francesca
; Ortu, Maria F
; Salvi, Erika
; Fresu, Giovanni
; Citterio, Lorena
; Braga, Daniele
; Piras, Daniela A
; Carpini, Simona Delli
; Velayutham, Dinesh
; Simonini, Marco
; Argiolas, Giuseppe
; Pozzoli, Simona
; Troffa, Chiara
; Glorioso, Valeria
; Kontula, Kimmo K
; Hiltunen, Timo P
; Donner, Kati M
; Turner, Stephen T
; Boerwinkle, Eric
; Chapman, Arlene B
; Padmanabhan, Sandosh
; Dominiczak, Anna F
; Melander, Olle
LU
; Johnson, Julie A
; Cooper-Dehoff, Rhonda M
; Gong, Yan
; Rivera, Natalia V
; Condorelli, Gianluigi
; Trimarco, Bruno
; Manunta, Paolo
; Cusi, Daniele
; Glorioso, Nicola
and Barlassina, Cristina
(Less) - organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Hypertension
- volume
- 33
- issue
- 6
- pages
- 1301 - 1309
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:25695618
- wos:000353819700026
- scopus:84929458153
- pmid:25695618
- ISSN
- 1473-5598
- DOI
- 10.1097/HJH.0000000000000541
- language
- English
- LU publication?
- yes
- id
- 113f79ce-557a-44d7-afed-1dfe59fba0e9 (old id 5143308)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25695618?dopt=Abstract
- date added to LUP
- 2016-04-01 09:53:15
- date last changed
- 2024-01-06 02:20:30
@article{113f79ce-557a-44d7-afed-1dfe59fba0e9,
abstract = {{Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment. Pharmacogenomics could be a useful tool to pinpoint gene variants involved in antihypertensive drug response, thus optimizing therapeutic advantages and minimizing side effects.}},
author = {{Chittani, Martina and Zaninello, Roberta and Lanzani, Chiara and Frau, Francesca and Ortu, Maria F and Salvi, Erika and Fresu, Giovanni and Citterio, Lorena and Braga, Daniele and Piras, Daniela A and Carpini, Simona Delli and Velayutham, Dinesh and Simonini, Marco and Argiolas, Giuseppe and Pozzoli, Simona and Troffa, Chiara and Glorioso, Valeria and Kontula, Kimmo K and Hiltunen, Timo P and Donner, Kati M and Turner, Stephen T and Boerwinkle, Eric and Chapman, Arlene B and Padmanabhan, Sandosh and Dominiczak, Anna F and Melander, Olle and Johnson, Julie A and Cooper-Dehoff, Rhonda M and Gong, Yan and Rivera, Natalia V and Condorelli, Gianluigi and Trimarco, Bruno and Manunta, Paolo and Cusi, Daniele and Glorioso, Nicola and Barlassina, Cristina}},
issn = {{1473-5598}},
language = {{eng}},
number = {{6}},
pages = {{1301--1309}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Journal of Hypertension}},
title = {{TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.}},
url = {{http://dx.doi.org/10.1097/HJH.0000000000000541}},
doi = {{10.1097/HJH.0000000000000541}},
volume = {{33}},
year = {{2015}},
}