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Independent validation of metric optimized gating for fetal cardiovascular phase-contrast flow imaging

Bidhult, Sebastian LU ; Töger, Johannes LU ; Heiberg, Einar LU ; Carlsson, Marcus LU ; Arheden, Håkan LU ; Aletras, Anthony H LU orcid and Hedström, Erik LU orcid (2019) In Magnetic Resonance in Medicine 81(1). p.495-503
Abstract

PURPOSE: To validate metric optimized gating phase-contrast MR (MOG PC-MR) flow measurements for a range of fetal flow velocities in phantom experiments. 2) To investigate intra- and interobserver variability for fetal flow measurements at an imaging center other than the original site.

METHODS: MOG PC-MR was compared to timer/beaker measurements in a pulsatile flow phantom using a heart rate (∼145 bpm), nozzle diameter (∼6 mm), and flow range (∼130-700 mL/min) similar to fetal imaging. Fifteen healthy fetuses were included for intra- and interobserver variability in the fetal descending aorta and umbilical vein.

RESULTS: Phantom MOG PC-MR flow bias and variability was 2% ± 23%. Accuracy of MOG PC-MR was degraded for flow... (More)

PURPOSE: To validate metric optimized gating phase-contrast MR (MOG PC-MR) flow measurements for a range of fetal flow velocities in phantom experiments. 2) To investigate intra- and interobserver variability for fetal flow measurements at an imaging center other than the original site.

METHODS: MOG PC-MR was compared to timer/beaker measurements in a pulsatile flow phantom using a heart rate (∼145 bpm), nozzle diameter (∼6 mm), and flow range (∼130-700 mL/min) similar to fetal imaging. Fifteen healthy fetuses were included for intra- and interobserver variability in the fetal descending aorta and umbilical vein.

RESULTS: Phantom MOG PC-MR flow bias and variability was 2% ± 23%. Accuracy of MOG PC-MR was degraded for flow profiles with low velocity-to-noise ratio. Intra- and interobserver coefficients of variation were 6% and 19%, respectively, for fetal descending aorta; and 10% and 17%, respectively, for the umbilical vein.

CONCLUSION: Phantom validation showed good agreement between MOG and conventionally gated PC-MR, except for cases with low velocity-to-noise ratio, which resulted in MOG misgating and underestimated peak velocities and warranted optimization of sequence parameters to individual fetal vessels. Inter- and intraobserver variability for fetal MOG PC-MR imaging were comparable to previously reported values.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Magnetic Resonance in Medicine
volume
81
issue
1
pages
495 - 503
publisher
John Wiley & Sons Inc.
external identifiers
  • pmid:30159933
  • scopus:85053281500
ISSN
1522-2594
DOI
10.1002/mrm.27392
language
English
LU publication?
yes
id
5176f8e6-31e8-4780-a004-d09508c248dd
date added to LUP
2018-10-06 07:14:39
date last changed
2024-04-01 11:48:10
@article{5176f8e6-31e8-4780-a004-d09508c248dd,
  abstract     = {{<p>PURPOSE: To validate metric optimized gating phase-contrast MR (MOG PC-MR) flow measurements for a range of fetal flow velocities in phantom experiments. 2) To investigate intra- and interobserver variability for fetal flow measurements at an imaging center other than the original site.</p><p>METHODS: MOG PC-MR was compared to timer/beaker measurements in a pulsatile flow phantom using a heart rate (∼145 bpm), nozzle diameter (∼6 mm), and flow range (∼130-700 mL/min) similar to fetal imaging. Fifteen healthy fetuses were included for intra- and interobserver variability in the fetal descending aorta and umbilical vein.</p><p>RESULTS: Phantom MOG PC-MR flow bias and variability was 2% ± 23%. Accuracy of MOG PC-MR was degraded for flow profiles with low velocity-to-noise ratio. Intra- and interobserver coefficients of variation were 6% and 19%, respectively, for fetal descending aorta; and 10% and 17%, respectively, for the umbilical vein.</p><p>CONCLUSION: Phantom validation showed good agreement between MOG and conventionally gated PC-MR, except for cases with low velocity-to-noise ratio, which resulted in MOG misgating and underestimated peak velocities and warranted optimization of sequence parameters to individual fetal vessels. Inter- and intraobserver variability for fetal MOG PC-MR imaging were comparable to previously reported values.</p>}},
  author       = {{Bidhult, Sebastian and Töger, Johannes and Heiberg, Einar and Carlsson, Marcus and Arheden, Håkan and Aletras, Anthony H and Hedström, Erik}},
  issn         = {{1522-2594}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{495--503}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Magnetic Resonance in Medicine}},
  title        = {{Independent validation of metric optimized gating for fetal cardiovascular phase-contrast flow imaging}},
  url          = {{http://dx.doi.org/10.1002/mrm.27392}},
  doi          = {{10.1002/mrm.27392}},
  volume       = {{81}},
  year         = {{2019}},
}