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The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.

Dahlman, I ; Sinha, I ; Gao, H ; Brodin, D ; Thorell, A ; Rydén, M ; Andersson, D P ; Henriksson, J ; Perfilyev, Alexander LU orcid and Ling, Charlotte LU orcid , et al. (2015) In International Journal of Obesity 39(6). p.910-919
Abstract
Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many small fat cells) in post-obesity.
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Journal of Obesity
volume
39
issue
6
pages
910 - 919
publisher
Nature Publishing Group
external identifiers
  • pmid:25783037
  • wos:000356039500006
  • scopus:84930764622
  • pmid:25783037
ISSN
1476-5497
DOI
10.1038/ijo.2015.31
language
English
LU publication?
yes
id
a83a8492-8a3d-4bfe-b5d1-a1cf942bdb1d (old id 5258315)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25783037?dopt=Abstract
date added to LUP
2016-04-01 09:57:51
date last changed
2022-09-18 01:08:45
@article{a83a8492-8a3d-4bfe-b5d1-a1cf942bdb1d,
  abstract     = {{Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many small fat cells) in post-obesity.}},
  author       = {{Dahlman, I and Sinha, I and Gao, H and Brodin, D and Thorell, A and Rydén, M and Andersson, D P and Henriksson, J and Perfilyev, Alexander and Ling, Charlotte and Dahlman-Wright, K and Arner, P}},
  issn         = {{1476-5497}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{910--919}},
  publisher    = {{Nature Publishing Group}},
  series       = {{International Journal of Obesity}},
  title        = {{The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.}},
  url          = {{http://dx.doi.org/10.1038/ijo.2015.31}},
  doi          = {{10.1038/ijo.2015.31}},
  volume       = {{39}},
  year         = {{2015}},
}