The Frontotemporal Dementias.
(2015) In Psychiatric Clinics of North America 38(2). p.193-193- Abstract
- Frontotemporal dementia (FTD) is a heterogeneous group of hereditary and sporadic neurodegenerative disorders affecting frontotemporal areas. FTD, a leading cause of young-onset dementia, is often initially mistaken for primary psychiatric disorders. Based on early and predominant symptoms, different clinical syndromes can be distinguished: the behavioral variant and 2 variants of progressive aphasia; semantic dementia and progressive nonfluent aphasia. Neuropathological classification is based on protein accumulation in the brain. Pathogenic mutations in different genes have been identified. Specific pharmacological treatment is the main research goal. Meanwhile the management must focus on early correct diagnosis, symptom alleviation,... (More)
- Frontotemporal dementia (FTD) is a heterogeneous group of hereditary and sporadic neurodegenerative disorders affecting frontotemporal areas. FTD, a leading cause of young-onset dementia, is often initially mistaken for primary psychiatric disorders. Based on early and predominant symptoms, different clinical syndromes can be distinguished: the behavioral variant and 2 variants of progressive aphasia; semantic dementia and progressive nonfluent aphasia. Neuropathological classification is based on protein accumulation in the brain. Pathogenic mutations in different genes have been identified. Specific pharmacological treatment is the main research goal. Meanwhile the management must focus on early correct diagnosis, symptom alleviation, caregiver support and educational interventions. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5442690
- author
- Landqvist, Maria LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Psychiatric Clinics of North America
- volume
- 38
- issue
- 2
- pages
- 193 - 193
- publisher
- Elsevier
- external identifiers
-
- pmid:25998110
- wos:000356634700002
- scopus:84929656224
- pmid:25998110
- ISSN
- 1558-3147
- DOI
- 10.1016/j.psc.2015.02.001
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Psychogeriatrics (013304000)
- id
- 0a596652-9912-4a6c-809e-c61dd148d7dc (old id 5442690)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25998110?dopt=Abstract
- date added to LUP
- 2016-04-01 10:33:52
- date last changed
- 2022-04-20 03:24:08
@article{0a596652-9912-4a6c-809e-c61dd148d7dc,
abstract = {{Frontotemporal dementia (FTD) is a heterogeneous group of hereditary and sporadic neurodegenerative disorders affecting frontotemporal areas. FTD, a leading cause of young-onset dementia, is often initially mistaken for primary psychiatric disorders. Based on early and predominant symptoms, different clinical syndromes can be distinguished: the behavioral variant and 2 variants of progressive aphasia; semantic dementia and progressive nonfluent aphasia. Neuropathological classification is based on protein accumulation in the brain. Pathogenic mutations in different genes have been identified. Specific pharmacological treatment is the main research goal. Meanwhile the management must focus on early correct diagnosis, symptom alleviation, caregiver support and educational interventions.}},
author = {{Landqvist, Maria}},
issn = {{1558-3147}},
language = {{eng}},
number = {{2}},
pages = {{193--193}},
publisher = {{Elsevier}},
series = {{Psychiatric Clinics of North America}},
title = {{The Frontotemporal Dementias.}},
url = {{http://dx.doi.org/10.1016/j.psc.2015.02.001}},
doi = {{10.1016/j.psc.2015.02.001}},
volume = {{38}},
year = {{2015}},
}