Innate and adaptive immunity in immune thrombocytopenia
(2013) In Seminars in Hematology 50(Suppl 1). p.68-70- Abstract
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by both accelerated clearance of autoantibody-sensitized platelets and suboptimal platelet production. A number of studies have provided evidence of disturbed innate and adaptive immune responses in patients with ITP. This brief review will highlight some of the more recent work in this field and highlight other findings that provide a potential link between ITP, systemic lupus erythematosus (SLE), and autoimmune hemolytic anemia (AHA).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5db58dc7-955f-4d6e-a3d8-ed09d739770c
- author
- Lazarus, Alan H ; Semple, John W LU and Cines, Douglas B
- publishing date
- 2013-01
- type
- Contribution to journal
- publication status
- published
- keywords
- Adaptive Immunity, Animals, Humans, Immunity, Innate, Thrombocytopenia, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
- in
- Seminars in Hematology
- volume
- 50
- issue
- Suppl 1
- pages
- 68 - 70
- publisher
- Elsevier
- external identifiers
-
- scopus:84877654040
- pmid:23664521
- ISSN
- 0037-1963
- DOI
- 10.1053/j.seminhematol.2013.03.012
- language
- English
- LU publication?
- no
- id
- 5db58dc7-955f-4d6e-a3d8-ed09d739770c
- date added to LUP
- 2016-09-23 12:02:27
- date last changed
- 2024-01-04 13:06:59
@article{5db58dc7-955f-4d6e-a3d8-ed09d739770c, abstract = {{<p>Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by both accelerated clearance of autoantibody-sensitized platelets and suboptimal platelet production. A number of studies have provided evidence of disturbed innate and adaptive immune responses in patients with ITP. This brief review will highlight some of the more recent work in this field and highlight other findings that provide a potential link between ITP, systemic lupus erythematosus (SLE), and autoimmune hemolytic anemia (AHA).</p>}}, author = {{Lazarus, Alan H and Semple, John W and Cines, Douglas B}}, issn = {{0037-1963}}, keywords = {{Adaptive Immunity; Animals; Humans; Immunity, Innate; Thrombocytopenia; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review}}, language = {{eng}}, number = {{Suppl 1}}, pages = {{68--70}}, publisher = {{Elsevier}}, series = {{Seminars in Hematology}}, title = {{Innate and adaptive immunity in immune thrombocytopenia}}, url = {{http://dx.doi.org/10.1053/j.seminhematol.2013.03.012}}, doi = {{10.1053/j.seminhematol.2013.03.012}}, volume = {{50}}, year = {{2013}}, }