Association between age and epididymal and accessory sex gland function and their relation to sperm motility
(2007) In Archives of Andrology 53(3). p.149-156- Abstract
- Increased male age has been associated with significant reduction in pregnancy rates. This study investigated the association between age, the function of epididymal and accessory sex glands, and their relation to sperm motility. Ejaculates from 498 men assessed for infertility were analysed according to WHO [1999] guidelines. Seminal markers of epididymal (neutral alpha-glucosidase (NAG)), prostatic (prostate-specific antigen (PSA) and zinc), and seminal vesicle function (fructose) were measured. Four groups according to age were defined: G(21-30) (21-30 years), G(31-40) (31-40 years), G(41-50) (41-50 years), and G(> 50) (51-66 years). Percentage progressive motility was significantly lower in G(> 50) compared with G21-30. NAG, PSA,... (More)
- Increased male age has been associated with significant reduction in pregnancy rates. This study investigated the association between age, the function of epididymal and accessory sex glands, and their relation to sperm motility. Ejaculates from 498 men assessed for infertility were analysed according to WHO [1999] guidelines. Seminal markers of epididymal (neutral alpha-glucosidase (NAG)), prostatic (prostate-specific antigen (PSA) and zinc), and seminal vesicle function (fructose) were measured. Four groups according to age were defined: G(21-30) (21-30 years), G(31-40) (31-40 years), G(41-50) (41-50 years), and G(> 50) (51-66 years). Percentage progressive motility was significantly lower in G(> 50) compared with G21-30. NAG, PSA, zinc, and fructose were significantly lower in G(> 50) compared with G21-30. In a multiple regression analysis model, NAG and PSA showed positive significant association with percentage progressive motility. The opposite trend was found regarding zinc. No association between fructose and percentage progressive motility was shown. In this cross-sectional study, declined sperm motility observed in men over 50 years of age might be due to age-dependent changes in epididymal and accessory sex gland function. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/647590
- author
- Elzanaty, Saad LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- epididymis, accessory sex gland, sperm motility, male age
- in
- Archives of Andrology
- volume
- 53
- issue
- 3
- pages
- 149 - 156
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000247731300005
- scopus:79961201011
- ISSN
- 0148-5016
- DOI
- 10.1080/01485010701225667
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- 0f91259d-e03e-42d8-ac3f-a1746c12bd2e (old id 647590)
- date added to LUP
- 2016-04-01 16:51:07
- date last changed
- 2022-01-28 22:34:06
@article{0f91259d-e03e-42d8-ac3f-a1746c12bd2e,
abstract = {{Increased male age has been associated with significant reduction in pregnancy rates. This study investigated the association between age, the function of epididymal and accessory sex glands, and their relation to sperm motility. Ejaculates from 498 men assessed for infertility were analysed according to WHO [1999] guidelines. Seminal markers of epididymal (neutral alpha-glucosidase (NAG)), prostatic (prostate-specific antigen (PSA) and zinc), and seminal vesicle function (fructose) were measured. Four groups according to age were defined: G(21-30) (21-30 years), G(31-40) (31-40 years), G(41-50) (41-50 years), and G(> 50) (51-66 years). Percentage progressive motility was significantly lower in G(> 50) compared with G21-30. NAG, PSA, zinc, and fructose were significantly lower in G(> 50) compared with G21-30. In a multiple regression analysis model, NAG and PSA showed positive significant association with percentage progressive motility. The opposite trend was found regarding zinc. No association between fructose and percentage progressive motility was shown. In this cross-sectional study, declined sperm motility observed in men over 50 years of age might be due to age-dependent changes in epididymal and accessory sex gland function.}},
author = {{Elzanaty, Saad}},
issn = {{0148-5016}},
keywords = {{epididymis; accessory sex gland; sperm motility; male age}},
language = {{eng}},
number = {{3}},
pages = {{149--156}},
publisher = {{Taylor & Francis}},
series = {{Archives of Andrology}},
title = {{Association between age and epididymal and accessory sex gland function and their relation to sperm motility}},
url = {{http://dx.doi.org/10.1080/01485010701225667}},
doi = {{10.1080/01485010701225667}},
volume = {{53}},
year = {{2007}},
}