Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients

Wassélius, Johan LU ; Malmstedt, Jonas ; Kalin, Bo ; Larsson, Stig LU ; Sundin, Anders ; Hedin, Ulf and Jacobsson, Hans (2008) In Journal of Nuclear Medicine 49(10). p.5-1601
Abstract

UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.

METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.

RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the... (More)

UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.

METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.

RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.

CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aged, Aged, 80 and over, Aneurysm, Aorta, Aortic Aneurysm, Abdominal, Blood Vessel Prosthesis, Diagnostic Imaging, Female, Fluorodeoxyglucose F18, Humans, Male, Middle Aged, Positron-Emission Tomography, Radiopharmaceuticals, Tomography, X-Ray Computed, Journal Article, Research Support, Non-U.S. Gov't
in
Journal of Nuclear Medicine
volume
49
issue
10
pages
5 pages
publisher
Society of Nuclear Medicine
external identifiers
  • scopus:53749090533
  • pmid:18794261
ISSN
0161-5505
DOI
10.2967/jnumed.108.053462
language
English
LU publication?
no
id
71008a2e-f8ea-463b-bfdf-af469fdbd7ad
date added to LUP
2016-10-14 09:58:01
date last changed
2024-03-07 13:57:16
@article{71008a2e-f8ea-463b-bfdf-af469fdbd7ad,
  abstract     = {{<p>UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.</p><p>METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.</p><p>RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.</p><p>CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.</p>}},
  author       = {{Wassélius, Johan and Malmstedt, Jonas and Kalin, Bo and Larsson, Stig and Sundin, Anders and Hedin, Ulf and Jacobsson, Hans}},
  issn         = {{0161-5505}},
  keywords     = {{Aged; Aged, 80 and over; Aneurysm; Aorta; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis; Diagnostic Imaging; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Journal Article; Research Support, Non-U.S. Gov't}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{5--1601}},
  publisher    = {{Society of Nuclear Medicine}},
  series       = {{Journal of Nuclear Medicine}},
  title        = {{High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients}},
  url          = {{http://dx.doi.org/10.2967/jnumed.108.053462}},
  doi          = {{10.2967/jnumed.108.053462}},
  volume       = {{49}},
  year         = {{2008}},
}