Noninvasive characterization of atrioventricular conduction in patients with atrial fibrillation.
(2015) In Journal of Electrocardiology 48(6). p.938-942- Abstract
- The atrioventricular (AV) node plays a fundamental role in patients with atrial fibrillation (AF), acting as a filter to the numerous irregular atrial impulses which bombard the node. A phenomenological approach to better understand AV nodal electrophysiology is to analyze the ventricular response with respect to irregularity. In different cohorts of AF patients, such analysis has been performed with the aim to evaluate the association between ventricular response characteristics and long-term clinical outcome and to determine whether irregularity is affected by rate-control drugs. Another approach to studying AV nodal characteristics is to employ a mathematical model which accounts for the refractory periods of the two AV nodal pathways.... (More)
- The atrioventricular (AV) node plays a fundamental role in patients with atrial fibrillation (AF), acting as a filter to the numerous irregular atrial impulses which bombard the node. A phenomenological approach to better understand AV nodal electrophysiology is to analyze the ventricular response with respect to irregularity. In different cohorts of AF patients, such analysis has been performed with the aim to evaluate the association between ventricular response characteristics and long-term clinical outcome and to determine whether irregularity is affected by rate-control drugs. Another approach to studying AV nodal characteristics is to employ a mathematical model which accounts for the refractory periods of the two AV nodal pathways. With atrial fibrillatory rate and RR intervals as input, the model has been considered for analyzing data during (i) rest and head-up tilt test, (ii) tecadenoson and esmolol, and (iii) rate-control drugs. The present paper provides an overview of our recent work on the characterization and assessment of AV nodal conduction using these two approaches. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8043602
- author
- Corino, Valentina D A ; Sandberg, Frida LU ; Mainardi, Luca T ; Platonov, Pyotr LU and Sörnmo, Leif LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Electrocardiology
- volume
- 48
- issue
- 6
- pages
- 938 - 942
- publisher
- Elsevier
- external identifiers
-
- pmid:26324177
- wos:000364896800004
- scopus:84952864656
- pmid:26324177
- ISSN
- 1532-8430
- DOI
- 10.1016/j.jelectrocard.2015.08.010
- language
- English
- LU publication?
- yes
- id
- 5568080a-1cbb-44db-9f99-5adc0a1e004e (old id 8043602)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26324177?dopt=Abstract
- date added to LUP
- 2016-04-01 10:11:09
- date last changed
- 2022-01-25 20:37:03
@article{5568080a-1cbb-44db-9f99-5adc0a1e004e,
abstract = {{The atrioventricular (AV) node plays a fundamental role in patients with atrial fibrillation (AF), acting as a filter to the numerous irregular atrial impulses which bombard the node. A phenomenological approach to better understand AV nodal electrophysiology is to analyze the ventricular response with respect to irregularity. In different cohorts of AF patients, such analysis has been performed with the aim to evaluate the association between ventricular response characteristics and long-term clinical outcome and to determine whether irregularity is affected by rate-control drugs. Another approach to studying AV nodal characteristics is to employ a mathematical model which accounts for the refractory periods of the two AV nodal pathways. With atrial fibrillatory rate and RR intervals as input, the model has been considered for analyzing data during (i) rest and head-up tilt test, (ii) tecadenoson and esmolol, and (iii) rate-control drugs. The present paper provides an overview of our recent work on the characterization and assessment of AV nodal conduction using these two approaches.}},
author = {{Corino, Valentina D A and Sandberg, Frida and Mainardi, Luca T and Platonov, Pyotr and Sörnmo, Leif}},
issn = {{1532-8430}},
language = {{eng}},
number = {{6}},
pages = {{938--942}},
publisher = {{Elsevier}},
series = {{Journal of Electrocardiology}},
title = {{Noninvasive characterization of atrioventricular conduction in patients with atrial fibrillation.}},
url = {{http://dx.doi.org/10.1016/j.jelectrocard.2015.08.010}},
doi = {{10.1016/j.jelectrocard.2015.08.010}},
volume = {{48}},
year = {{2015}},
}