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Radical pericardiectomy for chronic constrictive pericarditis

Nozohoor, Shahab LU ; Johansson, Maria ; Koul, Bansi LU and Cunha-Goncalves, Doris LU (2018) In Journal of Cardiac Surgery 33(6). p.301-307
Abstract

Background: We studied the impact of radical pericardiectomy on early and long-term patient survival, postoperative New York Heart Association (NYHA) functional class, and left ventricular ejection fraction in patients with chronic constrictive pericarditis compared to a sub-total pericardiectomy. Methods: From 1991 to 2016, 41 patients underwent pericardiectomy for chronic constrictive pericarditis. Sub-total pericardiectomy was performed in 17 (41%) and radical pericardiectomy in 24 (59%) patients. Patients in the two study groups had statistically similar NYHA functional class, left ventricular ejection fraction, and cardiac catheterization data. Follow-up was 100% complete with a median time of 4 years. Results: Radical... (More)

Background: We studied the impact of radical pericardiectomy on early and long-term patient survival, postoperative New York Heart Association (NYHA) functional class, and left ventricular ejection fraction in patients with chronic constrictive pericarditis compared to a sub-total pericardiectomy. Methods: From 1991 to 2016, 41 patients underwent pericardiectomy for chronic constrictive pericarditis. Sub-total pericardiectomy was performed in 17 (41%) and radical pericardiectomy in 24 (59%) patients. Patients in the two study groups had statistically similar NYHA functional class, left ventricular ejection fraction, and cardiac catheterization data. Follow-up was 100% complete with a median time of 4 years. Results: Radical pericardiectomy resulted in increased survival rates at 10 years (94%) compared to sub-total pericardiectomy (55%) (P = 0.014). In the idiopathic chronic constrictive pericarditis sub-group, long-term survival rates were also increased after a radical pericardiectomy (P = 0.001). Eighty-five percent of patients after a radical pericardiectomy were in NYHA functional class I or II after 5 years and 94% up to 25 years versus 53% and 63%, respectively, for the sub-total pericardiectomy group. Conclusions: Radical pericardiectomy provided superior 10-year survival and clinical functional improvement in patients with chronic constrictive pericarditis compared to sub-total pericaridectomy.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cardiac function, cardiac reoperation, outcomes, pericardium
in
Journal of Cardiac Surgery
volume
33
issue
6
pages
7 pages
publisher
Futura Publishing Company
external identifiers
  • scopus:85047638120
  • pmid:29761570
ISSN
0886-0440
DOI
10.1111/jocs.13715
language
English
LU publication?
yes
id
81709800-2875-427d-8421-310e1daa0c22
date added to LUP
2018-06-11 13:34:51
date last changed
2024-04-15 08:02:11
@article{81709800-2875-427d-8421-310e1daa0c22,
  abstract     = {{<p>Background: We studied the impact of radical pericardiectomy on early and long-term patient survival, postoperative New York Heart Association (NYHA) functional class, and left ventricular ejection fraction in patients with chronic constrictive pericarditis compared to a sub-total pericardiectomy. Methods: From 1991 to 2016, 41 patients underwent pericardiectomy for chronic constrictive pericarditis. Sub-total pericardiectomy was performed in 17 (41%) and radical pericardiectomy in 24 (59%) patients. Patients in the two study groups had statistically similar NYHA functional class, left ventricular ejection fraction, and cardiac catheterization data. Follow-up was 100% complete with a median time of 4 years. Results: Radical pericardiectomy resulted in increased survival rates at 10 years (94%) compared to sub-total pericardiectomy (55%) (P = 0.014). In the idiopathic chronic constrictive pericarditis sub-group, long-term survival rates were also increased after a radical pericardiectomy (P = 0.001). Eighty-five percent of patients after a radical pericardiectomy were in NYHA functional class I or II after 5 years and 94% up to 25 years versus 53% and 63%, respectively, for the sub-total pericardiectomy group. Conclusions: Radical pericardiectomy provided superior 10-year survival and clinical functional improvement in patients with chronic constrictive pericarditis compared to sub-total pericaridectomy.</p>}},
  author       = {{Nozohoor, Shahab and Johansson, Maria and Koul, Bansi and Cunha-Goncalves, Doris}},
  issn         = {{0886-0440}},
  keywords     = {{cardiac function; cardiac reoperation; outcomes; pericardium}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{6}},
  pages        = {{301--307}},
  publisher    = {{Futura Publishing Company}},
  series       = {{Journal of Cardiac Surgery}},
  title        = {{Radical pericardiectomy for chronic constrictive pericarditis}},
  url          = {{http://dx.doi.org/10.1111/jocs.13715}},
  doi          = {{10.1111/jocs.13715}},
  volume       = {{33}},
  year         = {{2018}},
}