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Increasing depth penetration in biological tissue imaging using 808-nm excited Nd3+/Yb3+/Er3+-doped upconverting nanoparticles

Soderlund, Hugo ; Mousavi, Monirehalsadat LU ; Liu, Haichun LU and Andersson-Engels, Stefan LU (2015) In Journal of Biomedical Optics 20(8).
Abstract
Ytterbium (Yb3+)-sensitized upconverting nanoparticles (UCNPs) are excited at 975 nm causing relatively high absorption in tissue. A new type of UCNPs with neodymium (Nd3+) and Yb3+ codoping is excitable at a 808-nm wavelength. At this wavelength, the tissue absorption is lower. Here we quantify, both experimentally and theoretically, to what extent Nd3+-doped UCNPs will provide an increased signal at larger depths in tissue compared to conventional 975-nm excited UCNPs. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
upconverting nanoparticles, tissue optics, deep tissue imaging
in
Journal of Biomedical Optics
volume
20
issue
8
article number
086008
publisher
SPIE
external identifiers
  • wos:000362516700019
  • scopus:84939250080
  • pmid:26271054
ISSN
1083-3668
DOI
10.1117/1.JBO.20.8.086008
language
English
LU publication?
yes
id
c2a987e5-f993-4442-9e5c-c8ea177bae93 (old id 8220515)
date added to LUP
2016-04-01 10:26:12
date last changed
2022-02-17 18:02:12
@article{c2a987e5-f993-4442-9e5c-c8ea177bae93,
  abstract     = {{Ytterbium (Yb3+)-sensitized upconverting nanoparticles (UCNPs) are excited at 975 nm causing relatively high absorption in tissue. A new type of UCNPs with neodymium (Nd3+) and Yb3+ codoping is excitable at a 808-nm wavelength. At this wavelength, the tissue absorption is lower. Here we quantify, both experimentally and theoretically, to what extent Nd3+-doped UCNPs will provide an increased signal at larger depths in tissue compared to conventional 975-nm excited UCNPs. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.}},
  author       = {{Soderlund, Hugo and Mousavi, Monirehalsadat and Liu, Haichun and Andersson-Engels, Stefan}},
  issn         = {{1083-3668}},
  keywords     = {{upconverting nanoparticles; tissue optics; deep tissue imaging}},
  language     = {{eng}},
  number       = {{8}},
  publisher    = {{SPIE}},
  series       = {{Journal of Biomedical Optics}},
  title        = {{Increasing depth penetration in biological tissue imaging using 808-nm excited Nd3+/Yb3+/Er3+-doped upconverting nanoparticles}},
  url          = {{http://dx.doi.org/10.1117/1.JBO.20.8.086008}},
  doi          = {{10.1117/1.JBO.20.8.086008}},
  volume       = {{20}},
  year         = {{2015}},
}