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Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia.

Inacio, Ana LU ; Liu, Yawei ; Clausen, Bettina H ; Svensson, Martina LU orcid ; Kucharz, Krzysztof LU ; Yang, Yiyi LU orcid ; Stankovich, Totte ; Khorooshi, Reza ; Lambertsen, Kate L and Issazadeh-Navikas, Shohreh , et al. (2015) In Journal of Neuroinflammation 12(1).
Abstract
Interferon (IFN)-β exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory condition of the central nervous system. Analogously, it has been hypothesized that IFN-β, by limiting inflammation, decreases neuronal death and promotes functional recovery after stroke. However, the core actions of endogenous IFN-β signaling in stroke are unclear.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Neuroinflammation
volume
12
issue
1
article number
211
publisher
BioMed Central (BMC)
external identifiers
  • pmid:26581581
  • wos:000364902200002
  • scopus:84960370618
  • pmid:26581581
ISSN
1742-2094
DOI
10.1186/s12974-015-0427-0
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Neuroinflammation (013210006), Faculty of Medicine (000022000), Laboratory for Experimental Brain Research (013041000)
id
ce6c86eb-b4e9-4880-b016-9701b7927404 (old id 8235218)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26581581?dopt=Abstract
date added to LUP
2016-04-01 13:42:15
date last changed
2024-01-24 13:54:39
@article{ce6c86eb-b4e9-4880-b016-9701b7927404,
  abstract     = {{Interferon (IFN)-β exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory condition of the central nervous system. Analogously, it has been hypothesized that IFN-β, by limiting inflammation, decreases neuronal death and promotes functional recovery after stroke. However, the core actions of endogenous IFN-β signaling in stroke are unclear.}},
  author       = {{Inacio, Ana and Liu, Yawei and Clausen, Bettina H and Svensson, Martina and Kucharz, Krzysztof and Yang, Yiyi and Stankovich, Totte and Khorooshi, Reza and Lambertsen, Kate L and Issazadeh-Navikas, Shohreh and Deierborg, Tomas}},
  issn         = {{1742-2094}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{Journal of Neuroinflammation}},
  title        = {{Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia.}},
  url          = {{http://dx.doi.org/10.1186/s12974-015-0427-0}},
  doi          = {{10.1186/s12974-015-0427-0}},
  volume       = {{12}},
  year         = {{2015}},
}