The Importance of Magnesium in the Human Body: A Systematic Literature review
(2016) 73. p.169-193- Abstract
- Magnesium, the second and fourth most abundant cation in the intracellular compartment and whole body, respectively, is of great physiologic importance. Magnesium exists as bound and free ionized forms depending on temperature, pH, ionic strength, and competing ions. Free magnesium participates in many biochemical processes and is most commonly measured by ion-selective electrode. This analytical approach is problematic because complete selectivity is not possible due to competition with other ions, i.e., calcium, and pH interference. Unfortunately, many studies have focused on measurement of total magnesium rather than its free bioactive form making it difficult to correlate to disease states. This systematic literature review presents... (More)
- Magnesium, the second and fourth most abundant cation in the intracellular compartment and whole body, respectively, is of great physiologic importance. Magnesium exists as bound and free ionized forms depending on temperature, pH, ionic strength, and competing ions. Free magnesium participates in many biochemical processes and is most commonly measured by ion-selective electrode. This analytical approach is problematic because complete selectivity is not possible due to competition with other ions, i.e., calcium, and pH interference. Unfortunately, many studies have focused on measurement of total magnesium rather than its free bioactive form making it difficult to correlate to disease states. This systematic literature review presents current analytical challenges in obtaining accurate and reproducible test results for magnesium. © 2016 Elsevier Inc. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8625900
- author
- Glasdam, Sidsel-Marie ; Glasdam, Stinne LU and Peters, Günther H.
- organization
- publishing date
- 2016
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- magmesium, human body, measurement
- host publication
- Advances in Clinical Chemistry
- editor
- Makowski, Gregory S.
- volume
- 73
- pages
- 169 - 193
- publisher
- Academic Press
- external identifiers
-
- scopus:84954271400
- pmid:26975973
- wos:000377029300007
- ISSN
- 0065-2423
- ISBN
- 978-0-12-804690-6
- DOI
- 10.1016/bs.acc.2015.10.002
- language
- English
- LU publication?
- yes
- id
- 5aa23e3e-96b1-4a8c-807b-e2bab6bc6e8f (old id 8625900)
- date added to LUP
- 2016-04-01 14:08:03
- date last changed
- 2022-04-22 01:28:37
@inbook{5aa23e3e-96b1-4a8c-807b-e2bab6bc6e8f,
abstract = {{Magnesium, the second and fourth most abundant cation in the intracellular compartment and whole body, respectively, is of great physiologic importance. Magnesium exists as bound and free ionized forms depending on temperature, pH, ionic strength, and competing ions. Free magnesium participates in many biochemical processes and is most commonly measured by ion-selective electrode. This analytical approach is problematic because complete selectivity is not possible due to competition with other ions, i.e., calcium, and pH interference. Unfortunately, many studies have focused on measurement of total magnesium rather than its free bioactive form making it difficult to correlate to disease states. This systematic literature review presents current analytical challenges in obtaining accurate and reproducible test results for magnesium. © 2016 Elsevier Inc.}},
author = {{Glasdam, Sidsel-Marie and Glasdam, Stinne and Peters, Günther H.}},
booktitle = {{Advances in Clinical Chemistry}},
editor = {{Makowski, Gregory S.}},
isbn = {{978-0-12-804690-6}},
issn = {{0065-2423}},
keywords = {{magmesium; human body; measurement}},
language = {{eng}},
pages = {{169--193}},
publisher = {{Academic Press}},
title = {{The Importance of Magnesium in the Human Body: A Systematic Literature review}},
url = {{http://dx.doi.org/10.1016/bs.acc.2015.10.002}},
doi = {{10.1016/bs.acc.2015.10.002}},
volume = {{73}},
year = {{2016}},
}